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ProteomicsEnsured auxin sensing by degron flexibility
Using a structural proteomics approach via chemical cross-linking combined with mass spectrometry (XL-MS), we have resolved SCFTIR auxin·AUX/IAA complex overall topology, and established the power of IDRs modulating auxin receptor assemblies.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2020-05-11 | PXD015285 | Pride
Auxin Cross-linking Iaa12 Auxin receptor Xl-ms Idrs Indole-3-acetic acid Aux/iaas Iaa7 Scf-type e3 ubiquitin ligase Tir1 
ProteomicsTurboID reveals the interaction network of VESICLE-INDUCING PROTEIN IN PLASTIDS (VIPPs) in Chlamydomonas reinhardtii
In Chlamydomonas reinhardtii, VIPP1 and VIPP2 play a role in the sensing and coping with membrane stress and in thylakoid membrane biogenesis. To gain more insight into these processes, we aimed to identify proteins interacting with VIPP1/2 in the chloroplast under ambient and H2O2 stress conditions...
ORGANISM(S): Chlamydomonas reinhardtii 
2024-01-26 | PXD038515 | Pride
Apex2 Vipp2 Vipp1 Chlamydomonas reinhardtii Turboid Lc-ms/ms 
TranscriptomicsSuppression of antitumor immunity by the oncometabolite 2-hydroxyglutarate
Isocitrate dehydrogenase (IDH) mutations, a hallmark of gliomagenesis, result in the production of the oncometabolite R-2-hydroxyglutarate (R-2-HG) which is thought to promote tumorigenesis via DNA methylation. Here we identify an additional immunosuppressive activity of R-2-HG: Tumor cell-derived R...
ORGANISM(S): Homo sapiens 
2016-07-27 | E-GEOD-84849 | biostudies-arrayexpress
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