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GenomicsThe Growth factor independence 1 (GFI1) 36N variant predisposes to Acute Myeloid Leukemia (AML) by inducing epigenetic changes at the Hoxa9 locus
GFI136N is a coding Single Nucleotide Polymorphism (SNP) in the gene GFI1 that increases the risk for Acute myeloid leukemia (AML) by 60%. It is present in 3-5% of Caucasians and has a prevalence of 12% among AML patients. We generated knockin mice expressing either the human GFI136N variant or the ...
ORGANISM(S): Mus musculus 
2012-12-04 | E-GEOD-31657 | biostudies-arrayexpress
TranscriptomicsChIP-chip by array of mouse cell lines and fresh tissues using anti-H3 trimethyl lysine 4.
Immunoprecipitations were performed using anti-H3 trimethyl lysine 4 (Millipore, 04-745 and gift from Dr. L. OM-oM->M-^RNeill, Birmingham, UK)
ORGANISM(S): Mus musculus 
2010-06-09 | E-MEXP-2665 | biostudies-arrayexpress
MetabolomicsComparative analysis of the adaptation of Staphylococcus aureus to internalization by different types of human non-professional phagocytic host cells (NMR assay)
Staphylococcus aureus is a human pathogen that can cause a wide range of diseases. Although formerly regarded as extracellular pathogen, it has been shown that S. aureus can also be internalized by host cells and persist within these cells. In the present study, we comparatively analyzed survival an...
2015-07-01 | MTBLS102 | MetaboLights
UnknownEnabling growth-decoupled Komagataella phaffii recombinant protein production based on the methanol-free PDH promoter.
Not available
S-EPMC10076887 | biostudies-literature
UnknownEfficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial.
Not available
S-EPMC8999864 | biostudies-literature
TranscriptomicsChIP-chip by array of mouse 416Bcell line using anti-PU.1 (Santa Cruz, sc-352X).
Immunoprecipitations were performed using anti-PU.1 (Santa Cruz, sc-352X)
ORGANISM(S): Mus musculus 
2011-04-07 | E-MEXP-2666 | biostudies-arrayexpress
TranscriptomicsChIP-chip by array of mouse cell lines and fresh tissue using anti-acetyl histone H3 antibody.
Immunoprecipitations were performed using anti-acetyl histone H3 antibody (Millipore, 06-599)
ORGANISM(S): Mus musculus 
2011-04-07 | E-MEXP-2664 | biostudies-arrayexpress
UnknownCrystal Structure and Magnetic Properties of Trinuclear Transition Metal Complexes (MnII, CoII, NiII and CuII) with Bridging Sulfonate-Functionalized 1,2,4-Triazole Derivatives.
Not available
S-EPMC8512707 | biostudies-literature
UnknownAcquisition Time for Swept-Source Optical Biometry Plus Corneal Power Measurement During Cataract Evaluation.
Not available
S-EPMC8906856 | biostudies-literature
UnknownTranslating medication effects for alcohol use disorder across preclinical, human laboratory, and clinical trial outcomes using meta-analysis.
Not available
S-EPMC12279940 | biostudies-literature
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