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TranscriptomicsTranscription profiling of rat ovary in culture reveals interactions between progesterone and tumor necrosis factor-alpha in the regulation of primordial follicle assembly
Follicle assembly is the process by which groups or ‘nests’ of oocytes break down to form primordial follicles. The size of the primordial follicle pool is the major determinant of the reproductive lifespan of a female. Previously, progesterone (P4) has been shown to inhibit follicle assembly,...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-8238 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat pooled untreated cultured ovaries vs. pooled cultured ovaries treated with anti-Mullerian hormone
The oocytes found within the primordial follicles of mammalian ovaries remain quiescent for months to years until they receive the appropriate signals to undergo the primordial to primary follicle transition and initiate folliculogenesis. The molecular mechanisms and extracellular signaling factors ...
ORGANISM(S): Rattus norvegicus 
2008-04-07 | E-GEOD-10557 | biostudies-arrayexpress
TranscriptomicsNeurotrophin NT3 promotes ovarian primordial to primary follicle transition
Neurotrophins are growth factors that are known to have a role in promoting cell survival and differentiation. The focus of the current study is to examine the role of neurotrophins in regulating ovarian primordial follicle development. Ovaries from 4-day old rats were placed into organ culture and ...
ORGANISM(S): Rattus norvegicus 
2010-02-21 | E-GEOD-20358 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat ovary during primordial follicle assembly and development.
The assembly of the developmentally arrested primordial follicle and subsequent transition to the primary follicle are poorly understood processes critical to ovarian biology. Abnormal primordial follicle development can lead to pathologies such as premature ovarian failure. The current study used a...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9300 | biostudies-arrayexpress
TranscriptomicsInhibitory Actions of Anti-MM-CM-
The current study was designed to investigate the actions of Anti-MM-CM-
ORGANISM(S): Rattus norvegicus 
2011-03-04 | E-GEOD-25629 | biostudies-arrayexpress
TranscriptomicsEnvironmentally Induced Epigenetic Transgenerational Inheritance of Ovarian Disease [NimbleGen]
The actions of environmental toxicants and relevant mixtures in promoting the epigenetic transgenerational inheritance of ovarian disease was investigated with the use of a fungicide, a pesticide mixture, a plastic mixture, dioxin and a hydrocarbon mixture. After transient exposure of an F0 gestatin...
ORGANISM(S): Rattus norvegicus 
2014-07-17 | E-GEOD-59277 | biostudies-arrayexpress
TranscriptomicsGene Bionetwork Analysis of Ovarian Primordial Follicle Development
Ovarian primordial follicles are critical for female reproduction and comprise a finite pool of gametes arrested in development. A systems biology approach was used to identify regulatory gene networks essential for primordial follicle development. Transcriptional responses to eight different growth...
ORGANISM(S): Rattus norvegicus 
2010-06-13 | E-GEOD-20324 | biostudies-arrayexpress
UnknownMotor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) after traumatic knee injury: study protocol for an adaptive randomized controlled trial.
Not available
S-EPMC8532360 | biostudies-literature
TranscriptomicsTranscription profiling of rat folliculogenesis reveals glial derived neurotrophic factor promotes ovarian primordial follicle development
Female fertility is determined in part by the size and development of the primordial follicle pool. The current study investigates the role of glial cell-line derived neurotrophic factor (GDNF) in the regulation of primordial follicle development in the ovary. Ovaries from four-day old female rat pu...
ORGANISM(S): Rattus norvegicus 
2008-06-11 | E-GEOD-11133 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Bos taurus granulosa and theca cells during ovarian antral follicle development.
Coordinated interactions between ovarian granulosa and theca cells are required for female endocrine function and fertility. To elucidate these interactions the regulation of the granulosa and theca cell transcriptomes during bovine antral follicle development were investigated. Granulosa cells and ...
ORGANISM(S): Bos taurus 
2008-11-04 | E-GEOD-11495 | biostudies-arrayexpress
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