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TranscriptomicsmiRNA profiling of GFAP+ cells isolated from GBM and adjacent non-tumor glial brain tissues
To identify miRNAs expression changes in human gliomas, weM-bM-^@M-^Bconducted a comprehensive microarray analysis to compare miRNAM-bM-^@M-^BexpressionM-bM-^@M-^BprofilesM-bM-^@M-^BinM-bM-^@M-^Bprimary cellsM-bM-^@M-^BobtainedM-bM-^@M-^BfromM-bM-^@M-^BmatchedM-bM-^@M-^BpairsM-bM-^@M-^BofM-bM-^@M-^B...
ORGANISM(S): Homo sapiens 
2013-03-01 | E-GEOD-44726 | biostudies-arrayexpress
ProteomicsGenomic regions flanking E-box sites influence DNA binding specificity of bHLH transcription factors through DNA shape (different concentrations)
DNA sequence is a major determinant of the binding specificity of transcription factors (TFs) for their genomic targets. However, eukaryotic cells often express, at the same time, TFs with highly similar DNA binding motifs but distinct in vivo targets. Currently, it is not well understood how TFs wi...
ORGANISM(S): Saccharomyces cerevisiae 
2013-03-29 | E-GEOD-44436 | biostudies-arrayexpress
TranscriptomicsChemosensitization of DLBCL cells in vitro and in vivo by demethylating nucleoside analogues [gene expression]
Silencing of genes that suppress the malignant phenotype by DNA methylation spurred an interest in the clinical use of epigenetic reprogramming agents. Single therapy is unlikely to be curative in the context of a heterogeneous disease such as Diffuse Large B cell Lymphomas (DLBCL). The combination ...
ORGANISM(S): Homo sapiens 
2012-07-29 | E-GEOD-28744 | biostudies-arrayexpress
TranscriptomicsTranscriptome analyses during fruiting body formation in Fusarium graminearum and Fusarium verticillioides reflect species life history and ecology
Fusarium graminearum and F. verticillioides are devastating cereal pathogens with very different life history and ecological characteristics. F. graminearum is homothallic, and sexual spores are an important component of its life cycle, responsible for disease initiation. F. verticilloides is hetero...
ORGANISM(S): Fusarium verticillioides 
2014-09-30 | E-GEOD-61865 | biostudies-arrayexpress
UnknownNr-CWS regulates METTL3-mediated m6A modification of CDS2 mRNA in vascular endothelial cells and has prognostic significance.
Not available
S-EPMC11489679 | biostudies-literature
MetabolomicsAn obligate aerobe adapts to hypoxia by hybridising fermentation with carbon storage
In soil ecosystems, obligately aerobic bacteria survive oxygen deprivation (hypoxia) by entering non-replicative persistent states. Little is known about how these bacteria rewire their metabolism to stay viable during persistence. The model obligate aerobe Mycobacterium smegmatis maintains redox ho...
2026-04-22 | MTBLS11404 | MetaboLights
UnknownEnzymatic Hydrolysis of Alginate to Produce Oligosaccharides by a New Purified Endo-Type Alginate Lyase.
Not available
S-EPMC4926067 | biostudies-literature
ProteomicsCellular and molecular responses of Cryptococcus to brilacidin (MMV1634402) and KIN1400 (MMV019724)
Cryptococcosis is a systemic mycosis caused by Cryptococcus neoformans and C. deuterogattii. Available therapeu-tic options are limited and face several challenges, including high toxicity, the emergence of resistant strains, high costs, and restrict-ed distribution. In this study, we evaluated the ...
ORGANISM(S): Cryptococcus neoformans H99-YPD_1 
2026-09-07 | PXD070309 | Pride
Cryptococcus neoformans Proteomics. Biofilm Cryptococcus deuterogattii Cryptococcosis Antifungal drugs syner-gism Antifungal activity 
MetabolomicsMetabolic and gut microbial remodeling in captive Amur tigers under uniform feeding

Ultra-high-performance liquid chromatography (UHPLC) was conducted using a Vanquish UHPLC system (Thermo Fisher), coupled with a Q Exactive™ HF/Q Exactive™ HF-X mass spectrometer for liquid chromatography-mass spectrometry (LC-MS) analysis. To ensure...

2026-06-05 | MTBLS14159 | MetaboLights
Proteomicsmass spectrometry analysis of in vitro kinase assay for DNA-PKcs and TAF7
To examine whether TAF7 could be phosphorylated by DNA-PKcs directly. An in vitro kinase assays were performed. Firstly, human DNA-PKcs was purified from TGF1 treated HK2 cells by immunoprecipitation with a DNA-PKcs antibody (abcam) and IgG was used as a negative control. The purified proteins and ...
ORGANISM(S): Homo Sapiens 
2022-09-22 | PXD036930 |
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