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TranscriptomicsRNA-seq of human NSCL cell lines with induced fusion genes; ALK-EML4-V1, ALK-EML4-V3, ALK-TFG, ALK-KIF5B
To characterize the effects of common ALK fusion genes, we performed a comprehensive RNA-Seq analysis of NL20 cells induced with ALK-EML4-V1, ALK-EML4-V3, ALK-TFG, ALK-KIF5B, using Doxycycline
ORGANISM(S): Homo sapiens 
2022-12-18 | E-MTAB-11304 | biostudies-arrayexpress
UnknownIn vitro and in vivo characterization of a novel West Nile virus lineage 2 strain.
Not available
S-EPMC11721649 | biostudies-literature
UnknownCytotoxic and Antioxidant Activity of a Set of Hetero Bicylic Methylthiadiazole Hydrazones: A Structure-Activity Study.
Not available
S-EPMC4499575 | biostudies-literature
ProteomicsALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression
Anaplastic lymphoma kinase (ALK) fusion variants in non-small-cell-lung cancer (NSCLC) consist of numerous dimerising fusion partners, with the most common being EML4. Clinical data suggests that the degree of treatment benefit in response to ALK tyrosine kinase inhibitors (TKIs) differs among the v...
ORGANISM(S): Homo sapiens (Human) 
2023-02-16 | PXD035100 | Pride
Human Nsclcl Orbitrap fusion lumos 
GenomicsRNA-seq of human NSCL cell lines with induced fusion genes ALK-EML4-V1, ALK-EML4-V3, ALK-TFG, ALK-KIF5B
RNA-seq of human NSCL cell lines with induced fusion genes ALK-EML4-V1, ALK-EML4-V3, ALK-TFG, ALK-KIF5B
PRJEB50074 | ENA
UnknownCrystalline silica-exposed human lung epithelial cells presented enhanced anchorage-independent growth with upregulated expression of BRD4 and EZH2 in autocrine and paracrine manners.
Not available
S-EPMC10162546 | biostudies-literature
UnknownAP205 VLPs Based on Dimerized Capsid Proteins Accommodate RBM Domain of SARS-CoV-2 and Serve as an Attractive Vaccine Candidate.
Not available
S-EPMC8073683 | biostudies-literature
UnknownMacrocybin, a Natural Mushroom Triglyceride, Reduces Tumor Growth In Vitro and In Vivo through Caveolin-Mediated Interference with the Actin Cytoskeleton.
Not available
S-EPMC7766322 | biostudies-literature
ProteomicsIntegrative multi-omic analysis of the SWI/SNF complex defines a new clinical subgroup of lung adenocarcinoma patients
Mammalian SWI/SNF complexes are ATP-dependent chromatin remodelers composed of varying combinations of subunits that, together, fine-tune transcriptional regulation and genome integrity. SWI/SNF complex subunits have been identified as major targets of mutations in several tumor types suggesting a r...
ORGANISM(S): Homo sapiens (Human) 
2022-04-01 | PXD017397 | Pride
Brg1 Ip Nl20 
GenomicsThe profile of circular RNA in lung cancer cell lines
The profile of circular RNA in lung cancer cell lines
PRJNA760444 | ENA
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