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NLC are generated from the in vitro culture of PBMC from CLL patients. These NLC derived from the differentiation of blood monocytes in contact with blood leukemic cells, We used microarrays to detail the global programme of NLC gene expression compared to monocytes gene expression.
ORGANISM(S): Homo sapiens 
2016-10-12 | GSE87813 | GEO
The study of the roles of macrophages in the microenvironment of cancer cells (tumor-associated macrophages, TAM) has gained deep insight over the recent years. Here, we describe gene expression profile of chronic lymphocytic leukemia (CLL)-associated macrophages, also called nurse-like cells (NLC),...
ORGANISM(S): Homo sapiens 
In the marrow and lymphatic tissues, chronic lymphocytic leukemia (CLL) cells interact with accessory cells that constitute the leukemia microenvironment. In lymphatic tissues, CLL cells are interspersed with CD68+ nurselike cells (NLC) and T cells. However, the mechanism regulating co-localization ...
ORGANISM(S): Homo sapiens 
The study of the roles of macrophages in the microenvironment of cancer cells (tumor-associated macrophages, TAM) has gained deep insight over the recent years. Here, we describe gene expression profile of chronic lymphocytic leukemia (CLL)-associated macrophages, also called nurse-like cells (NLC),...
ORGANISM(S): Homo sapiens 
2012-12-11 | GSE42733 | GEO
Liquid chromatography-mass spectrometry (LC-MS) is a major tool for large scale qualitative and/or quantitative analysis of protein phosphorylation in cells or tissues. Performance of LC is pivotal for the success of phosphoprotemics in both sensitivity and reproducibility. Here we report that the w...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) Homo sapiens (Human) 
2023-03-10 | PXD034396 | Pride
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