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GenomicsATRX tolerates activity-dependent histone H3 M-bM-^@M-^\methyl/phos switchingM-bM-^@M-^] to maintain repetitive element silencing in neurons
ATRX is a member of the SWI2/SNF2 family of chromatin remodeling proteins and primarily functions at heterochromatic loci via its recognition of M-bM-^@M-^XrepressiveM-bM-^@M-^Y histone modifications (e.g., H3K9me3). Despite significant roles for ATRX during normal neural development, as well as its...
ORGANISM(S): Mus musculus 
2015-01-02 | E-GEOD-64062 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiles of psychostimulant reinforcement in rats
Drug-induced alterations in transcriptional regulation play a central role in establishing the persistent neuroplasticities that occur during drug addiction. Additionally, changes in gene expression associated with drug administration provide valuable insight into the molecular basis of drug abuse. ...
ORGANISM(S): Rattus norvegicus 
2013-06-27 | E-GEOD-43748 | biostudies-arrayexpress
UnknownMechanochemical synthesis of Li₂MnO₃ shell/LiMO₂ (M = Ni, Co, Mn) core-structured nanocomposites for lithium-ion batteries.
Not available
S-EPMC4007074 | biostudies-literature
UnknownEditor's Highlight: Microbial-Derived 1,4-Dihydroxy-2-naphthoic Acid and Related Compounds as Aryl Hydrocarbon Receptor Agonists/Antagonists: Structure-Activity Relationships and Receptor Modeling.
Not available
S-EPMC5291215 | biostudies-literature
UnknownSALM4 regulates angiogenic functions in endothelial cells through VEGFR2 phosphorylation at Tyr1175.
Not available
S-EPMC6704462 | biostudies-literature
ModelsAbu-Soud1999_NOHArginine
This model is taken from the Abu-Soud HM et al. Biochemistry. 1999 Sep 21;38(38):12446-51. This model shows kinetic binding of NOHArginine to neuronal nitric oxide synthase. Model shows the substrate (NOH-Arginine) binding to nNOS in a two-step reversible fashion. First there is rapid binding equili...
2005-01-01 | MODEL9088294310 | BioModels
UnknownIL-10 prevents aging-associated inflammation and insulin resistance in skeletal muscle.
Not available
S-EPMC5240661 | biostudies-literature
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | E-GEOD-70279 | biostudies-arrayexpress
UnknownGeneration of recombination activating gene-1-deficient neonatal piglets: a model of T and B cell deficient severe combined immune deficiency.
Not available
S-EPMC4249935 | biostudies-literature
TranscriptomicsDynamics of gene expression changes in epithelial and mesenchymal HMLER cell lines transitioning from suspension 3D culture to adhesion cultures
In order to metastasize, few cells need to detach from the primary tumor, and transition through the circulation to distant sites to establish new solid tumor metastases. The gene expression changes occurring between these transitions are poorly understood, and controversial findings have been repor...
ORGANISM(S): Homo sapiens 
2015-07-10 | GSE70279 | GEO
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