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MetabolomicsNon-invasive urinary metabolomic profiles discriminate biliary atresia from infantile hepatitis syndrome
INTRODUCTION: Neonatal cholestatic disorders are a group of hepatobiliary diseases occurring in the first 3 months of life. The most common causes of neonatal cholestasis are infantile hepatitis syndrome (IHS) and biliary atresia (BA). The clinical manifestations of the two diseases are ...
2019-06-25 | MTBLS689 | MetaboLights
MetabolomicsUrinary Extracellular Vesicle Metabolomic Profiling Reveals a Distinct Molecular Signature for the Non-Invasive Diagnosis of Lupus Nephritis

Background: Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE), underscoring an urgent need for non-invasive diagnostic biomarkers. 

Objective: This study aimed to define the metabolomic signature of urinary e...

2026-02-11 | MTBLS13839 | MetaboLights
MetabolomicsNon-invasive urinary metabolomic profiling identifies diagnostic and prognostic markers in lung cancer
Lung cancer remains the most common cause of cancer deaths worldwide, yet there is currently a lack of diagnostic noninvasive biomarkers that could guide treatment decisions. Small molecules (<1500 Da) were measured in urine collected from 469 lung cancer patients and 536 population controls using u...
2014-05-06 | MTBLS28 | MetaboLights
TranscriptomicsCpG Methylation profile of Invasive Prostate Cancer Cells compared to Non-invasive
Two established cell lines, LNCaP and DU145 and two primary prostate cancer cell lines, PCSC1-2 were invaded toward a stem cell media through Matrigel. DNA was isolated from Non-invasive cells and invasive cells. Methylated DNA was isolated from each sample using the Methyl Collector kit from Active...
ORGANISM(S): Homo sapiens 
2010-12-04 | E-GEOD-25824 | biostudies-arrayexpress
TranscriptomicsCpG Methylation profile of Invasive Pancreatic Cancer Cells compared to Non-invasive
Two established cell lines, PANC1 and HPAC, were invaded toward a stem cell media through Matrigel. DNA was isolated from Non-invasive cells and invasive cells. Methylated DNA was isolated from each sample using the Methyl Collector kit from Active Motif. Methylated and Non-Methylated DNA was dye la...
ORGANISM(S): Homo sapiens 
2013-06-01 | E-GEOD-38076 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human invasive and non-invasive non-functioning pituitary adenomas
Context : Non Functioning Pituitary Adenomas (NFPAs), although typically benign, may be locally invasive. Few datas are currently available related to the molecular process of invasion in sporadic pituitary adenomas. Markers of invasiveness, important for helping the clinician in the therapeutic s...
ORGANISM(S): Homo sapiens 
2010-03-18 | E-TABM-899 | biostudies-arrayexpress
ProteomicsSmell of Infection: a novel, non-invasive method for detection of fish excretory- secretory proteins
Chemical signals are produced by aquatic organisms following predatory attacks or perturbations such as parasitic infection. Ectoparasites feeding on host fish are likely to cause release of similar alarm cues into the environment due to the stress, wounding and immune response stimulated upon infec...
ORGANISM(S): Kryptolebias marmoratus 
2019-01-02 | PXD010987 | Pride
Gel free ms Alarm cues Parasitic infection 
ProteomicsMenstrual fluid-derived extracellular vesicles as a non-invasive diagnostic tool for endometriosis
Introduction: Endometriosis is a debilitating condition where endometrial-like tissue grows outside the uterus and rarely in distant sites such as the lungs, heart and brain. Symptoms are severe chronic pain, bladder/bowel problems, painful sex and infertility. Differences in endometrium between wom...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD042101 | Pride
Endometriosis Extracellular vesicles Non-invasive diagnosis Menstrual fluid 
ProteomicsProteomic Analysis of Wharton’s Jelly Mesenchymal Stem Cells Isolated by Different Methods
Wharton’s Jelly mesenchymal stem cells (WJ-MSC) are stem cells from the umbilical cord, known for their regenerative properties. They offer advantages like unlimited availability, non-invasive and low-cost isolation, and minimal ethical concerns. WJ-MSCs are promising for allogeneic cell therapy, wi...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD063958 | Pride
Wharton’s jelly mesenchymal stem cells Proteomic Isolation methods 
ProteomicsNon-invasive biomarker discovery in hereditary angioedema
Hereditary angioedema (HAE) is a rare and potentially life-threatening disease. The pathogenesis of HAE is not well understood. Moreover, non-invasive disease biomarkers are strongly needed for early diagnosis and clinical management of HAE.
ORGANISM(S): Homo Sapiens 
PXD045435 |
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