Nonsynaptic mitochondria

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Social isolation stress-resilient rats reveal energy metabolic shift in hippocampal nonsynaptic mitochondria

We investigated the relative quantification of proteins in hippocampal cytosolic and nonsynaptic mitochondrial (NSM) fractions of rats exposed to chronic social isolation (CSIS), an animal model of depression, comparing CSIS-resilient with CSIS-sensitive or control rats, via a comparative subproteom...

ORGANISM(S): Rattus norvegicus (Rat)

2020-05-25 | PXD016966 | Pride

Quantitative proteomics of synaptic and nonsynaptic mitochondria: insights for synaptic mitochondrial vulnerability.

Not available

S-EPMC4015687 | biostudies-literature

Proteomic Signatures of Hippocampal Nonsynaptic and Synaptosome-Enriched Mitochondria in Rats Resilient to Chronic Social Isolation.

Not available

S-EPMC12564099 | biostudies-literature

Proteomics profiling of Neuronal Mitochondria

Mitochondria are the ‘power-houses’ of all cells, generating ATP to fuel numerous pathways which are vital for cellular form and function (1). Neuronal processes and synapses present a constant demand for ATP to maintain ionic gradients and neurotransmission events (2), promoting sub-populations of ...

ORGANISM(S): Rattus norvegicus (Rat)

2018-10-26 | PXD005537 | Pride

Neuron Proteomics Mitochondria Synapse Neurodegeneration

Deletion of mitochondrial calcium uniporter incompletely inhibits calcium uptake and induction of the permeability transition pore in brain mitochondria.

Not available

S-EPMC6177608 | biostudies-literature

Ca(2+) handling in isolated brain mitochondria and cultured neurons derived from the YAC128 mouse model of Huntington's disease.

Not available

S-EPMC4516671 | biostudies-literature

Unveiling a key role of oxaloacetate-glutamate interaction in regulation of respiration and ROS generation in nonsynaptic brain mitochondria using a kinetic model.

Not available

S-EPMC8330910 | biostudies-literature