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ProteomicsData and Information collection on 3 normal rat kidney epithelial cells treated with staurosporine
3 normal rat kidney epithelial cells treated with staurosporine,LC-MS/MS.
ORGANISM(S): Rattus norvegicus (Rat) 
2023-10-19 | PXD039380 | Pride
Lc-ms/ms Normal rat kidney epithelial cells 
TranscriptomicsExpression data from renal primary epithelial cells
Autosomal dominant polycystic kidney disease (ADPKD) is characterized by the formation of multiple fluid-filled cysts that destroy the kidney architecture resulting in end-stage renal failure. Mutations in the ADPKD genes PKD1 and PKD2 account for nearly all the cases of ADPKD. Increased cell prolif...
ORGANISM(S): Rattus norvegicus 
2010-05-19 | E-GEOD-11500 | biostudies-arrayexpress
MetabolomicsMesenchymal stromal cells secretome restores bioenergetic and redox homeostasis in human proximal tubule cells after ischemic injury

BACKGROUND: Ischemia/reperfusion injury (IRI) is the leading cause of acute kidney injury (AKI). The current standard of care focuses on supporting kidney function, stating the need for more efficient and targeted therapies to enhance repair. Mesenchymal Stromal Cells (MSCs) and ...

2023-10-16 | MTBLS6279 | MetaboLights
TranscriptomicsTranscription profiling of rat embryonic kidney timepoints and a budded WD-MM recombination tissue
Here we compared the expression of an engineered kidney tissue, created by recombining an in vitro budded Wolffian duct with fresh E13 metanephric mesenchyme, with that of three in vivo rat embryonic kidney timepoints (E13, E18, and week 4) Experiment Overall Design: The global gene expression of re...
ORGANISM(S): Rattus norvegicus 
2008-06-16 | E-GEOD-9570 | biostudies-arrayexpress
ProteomicsQuantitative proteomic analysis of CKD urine samples
Urinary proteomics studies have primarily focused on identifying markers of chronic kidney disease (CKD) progression. Here, we aimed to specify CKD-related injury markers through proteomics analysis in urine of patients with CKD. Label-free quantitative proteomics analysis based on liquid chromatogr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-06-15 | MSV000087635 | MassIVE
TranscriptomicsGene expression in rat kidney following recovery from acute renal failure (ARF)
This experiment was designed to study the alteration in expression of mRNA is kidney following recovery from transient acute renal failure. The model used was a 52 min. bilateral renal artery clamping, followed by reperfusion, which resulted in a transient loss of renal function, followed by a func...
ORGANISM(S): Rattus norvegicus 
2010-06-10 | E-GEOD-1714 | biostudies-arrayexpress
TranscriptomicsExpression data from kidneys of rats with and without cisplatin treatment
We investigated an acute kidney injury (AKI) model in rats induced by cisplatin (Cp) administration. The cisplatin is widely used since its biochemical and histopathological characteristics are representative of drug-induced AKI in humans. Male Wistar rats were dosed once ip with 0, 1 and 3 mg/kg ...
ORGANISM(S): Rattus norvegicus 
2016-08-23 | E-GEOD-85957 | biostudies-arrayexpress
TranscriptomicsRNA-seq of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
This experiment investigates the expression characteristics of residual breast cancer cells. Primary mammary epithelial cells taken from female mice with doxycycline-inducible hMyc- and Neu/Her2-oncogenes were grown in 3D organoid cultures. Upon the addition of doxycycline (200ng/mL) to the medium t...
ORGANISM(S): Mus musculus 
2020-12-31 | E-MTAB-8834 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human kidney glomerular and tubular progenitor cells
Multipotent progenitor cells (MPs) have been observed in human kidneys and particularly in Bowman's capsule and proximal tubules. The kidney owns the ability to repair local damage and renal MPs may play a role in the regenerative processes. Microarray technology was applied to identify differential...
ORGANISM(S): Homo sapiens 
2009-11-09 | E-GEOD-8611 | biostudies-arrayexpress
GenomicsEnzymatic Methyl-seq (EM-seq) of doxycycline induced tumor and residual mouse primary mammary epithelial cells grown in 3D cell cultures against non-induced controls
This experiment investigates the genome wide DNA methylation landscape of residual breast cancer cells. Primary mammary epithelial cells taken from female mice with doxycycline-inducible hMyc- and Neu/Her2-oncogenes were grown in 3D organoid cultures. Upon the addition of doxycycline (200ng/mL) to t...
ORGANISM(S): Mus musculus 
2021-10-03 | E-MTAB-10979 | biostudies-arrayexpress
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