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GenomicsTranslation switch from initiation to elongation needs Not4 and Not5 collaboration
Translation switch from initiation to elongation needs Not4 and Not5 collaboration
PRJNA566006 | ENA
UnknownThe Not5 subunit of the ccr4-not complex connects transcription and translation.
Not available
S-EPMC4207488 | biostudies-literature
TranscriptomicsTranslation switch from initiation to elongation needs Not4 and Not5 collaboration
Not4 and Not5 are crucial components of the Ccr4-Not complex with pivotal functions in mRNA metabolism. Both associate with ribosomes but mechanistic insights on their function remain elusive. Here we determine that Not5 and Not4 synchronously impact translation initiation and Not5 alone alters tran...
ORGANISM(S): Saccharomyces cerevisiae 
2021-08-18 | GSE137613 | GEO
GenomicsTrancriptome-wide association of Not1and Polysomal occupancy in wt and not5 background
Trancriptome-wide association of Not1and Polysomal occupancy in wt and not5 background
PRJEB8204 | ENA
ProteomicsMass Spectrometry of NOT gene-related purifications
Mass Spectrometry of NOT gene-related purifications, including NOT5 Tap Tag in WT and not4 deletion, the Ribosome Nascent Chain Complex, and aggregates in NOT5 Delta,
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-07-26 | PXD021580 | Pride
Aggregates Not5 Mass spectrometry Not4 Not genes Rnc Ribosome-nascent chain complex 
ProteomicsYeast not5 mutant protein translation analysis
Analysis of translation rate and turnover differences between wild type and not5 mutant yeast using pulse-chase mass spectrometry.
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2016-06-01 | PXD003871 | Pride
Silac Turnover Protein synthesis Yeast 
TranscriptomicsTrancriptome-wide association of Not1and Polysomal occupancy in wt and not5 background
The following data contains sequencing files for RNA IP and Polysome profiling experiments in wt and not5delta strains with background of Not1-TAP tagged strain (MAT_ leu2_20 ura3_ met15_ lys2_ his3delta1 not1::NOT1-Tap-tag-URA3). The RNA IP experiments have been performed as described previously (G...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-19 | E-MTAB-3195 | biostudies-arrayexpress
GenomicsNot4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A
Not4 and Not5 modulate translation elongation by Rps7A ubiquitination, Rli1 moonlighting, and condensates that exclude eIF5A
PRJNA565947 | ENA
UnknownNot5-dependent co-translational assembly of Ada2 and Spt20 is essential for functional integrity of SAGA.
Not available
S-EPMC5388395 | biostudies-literature
TranscriptomicsSpecific Roles for the Ccr4-Not Complex Subunits in Expression of the Genome
These Affymetrix data were used to determine the role of each non-essential subunit of the conserved Ccr4-Not complex in the control of gene expression in the yeast S. cerevisiae. The study was performed with cells growing exponentially in high glucose and with cells grown to glucose depletion. Spec...
ORGANISM(S): Saccharomyces cerevisiae 
2008-12-10 | E-GEOD-10521 | biostudies-arrayexpress
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