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ProteomicsPlasma Proteome adaptations in Feminising Gender Affirming Hormone therapy and Pregnancy
The dataset consists of longitudinal plasma proteomic data was generated using the Olink proteomics platform in plasma from transgender individuals receiving feminizing gender-affirming hormone therapy (GAHT). There were two treatment arms in the clinical trial that received different anti-androgens...
ORGANISM(S): Homo sapiens (Human) 
2025-09-17 | PAD000016 | Pride
Sex hormones Estradiol Gaht Pregnancy Sex Testosterone Gender Anti-androgen 
TranscriptomicsNeonatal DNA methylation profile in humans is specified by a complex interplay between intrauterine environmental/ genetic factors subject to tissue-specific influence
Comparison between groups of monozygotic (MZ) and dizygotic (DZ) twins enables an estimation of the relative contribution of genetic, shared and non-shared environmental factors to phenotypic variability. Using DNA methylation profiling of ~20,000 CpG sites as a phenotype, we have examined discordan...
ORGANISM(S): Homo sapiens 
2012-07-17 | E-GEOD-36642 | biostudies-arrayexpress
TranscriptomicsWide ranging DNA methylation differences of primary trophoblast cell populations and derived-cell lines
Difficulties associated with long term culture of primary trophoblasts have proven to be a major hurdle in their functional characterization. In order to circumvent this issue, several model cell lines have been established over many years using a variety of different approaches. Due to their differ...
ORGANISM(S): Homo sapiens 
2011-01-20 | E-GEOD-26683 | biostudies-arrayexpress
TranscriptomicsEvidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors.
Background: the human placenta facilitates the exchange of nutrients, gas and waste between the fetal and maternal circulations. It also protects the fetus from the maternal immune response. Due to its role at the feto-maternal interface, the placenta is subject to many environmental exposures that ...
ORGANISM(S): Homo sapiens 
2011-08-31 | E-GEOD-31781 | biostudies-arrayexpress
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