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ProteomicsOxidative Stress and Metabolic Plasticity of NOX-2 KO mice Hematopoitic Stem Cells Homeostasis Proteomics Profile
We investigated the contribution of NOX-2 to redox balance, mitochondrial respiration, and glycolytic compensation in lineage-negative Sca-1⁺c-Kit⁺ (SKL) bone marrow stem cells from wild-type (WT) and NOX-2 knockout (NOX2-KO) mice. Proteomic profiling identified differentially expressed proteins inv...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-03 | PXD066664 | Pride
Hematopoitic stem cells Nox-2 ko Nox-2 Proteomics Metabolic plasticity 
UnknownCB1 Receptor Activation Provides Neuroprotection in an Animal Model of Glutamate-Induced Excitotoxicity Through a Reduction of NOX-2 Activity and Oxidative Stress.
Not available
S-EPMC11534500 | biostudies-literature
TranscriptomicsPhagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
Here, we investigated the role of mononuclear phagocytes associated nicotinamide adenine dinucleotide phosphate oxidase 2 (NOX-2) in inflammatory neurodegeneration. Cybb-deficient mice NOX-2 knock-out (KO) and control wild type (WT) mice were treated intraperitoneally daily over four consecutive day...
ORGANISM(S): Mus musculus 
2020-08-03 | GSE153369 | GEO
UnknownBroad suppression of NADPH oxidase activity exacerbates ischemia/reperfusion injury through inadvertent downregulation of hypoxia-inducible factor-1α and upregulation of peroxisome proliferator-activated receptor-α.
Not available
S-EPMC3871171 | biostudies-literature
GenomicsPhagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
Phagocytosis-related NADPH oxidase 2 subunit gp91phox contributes to neurodegeneration after repeated systemic challenge with lipopolysaccharides
PRJNA642158 | ENA
UnknownSex-Dependent Effects of Nephron Ift88 Disruption on BP, Renal Function, and Cystogenesis.
Not available
S-EPMC8729858 | biostudies-literature
UnknownRole of NADPH oxidase-2 in the progression of the inflammatory response secondary to striatum excitotoxic damage.
Not available
S-EPMC6471795 | biostudies-literature
UnknownInsulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4.
Not available
S-EPMC5699944 | biostudies-literature
UnknownDefect in Migration of HSPCs in Nox-2 Deficient Mice Explained by Impaired Activation of Nlrp3 Inflammasome and Impaired Formation of Membrane Lipid Rafts.
Not available
S-EPMC11762604 | biostudies-literature
TranscriptomicsMurine pulmonary arterial smooth muscle cells: Wild-type vs. NOX1 deficiency (mRNA profiling)
NOX1 is a catalytic subunit of nonphagocytic NADPH oxidase, mainly localized to smooth muscle cells in the vasculature. We investigated the pathology underlying the pulmonary arterial hypertension-like phenotype demonstrated in mice deficient in the Nox1 gene (Nox1-KO). Spontaneous enlargement and h...
ORGANISM(S): Mus musculus 
2014-01-22 | E-GEOD-42014 | biostudies-arrayexpress
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