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The adaptor protein NTAL (non-T cell activation linker) is expresses in acute myeloid leukemia blasts, and its downregulation by alkylphospholipid treatment or protein expression knockdown reduces AKT activation. This new data elucidates new NTAL protein interactions.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD005850 | Pride
Non-T cell activation linker (NTAL, also called Lab or LAT2) is a transmembrane adaptor protein involved in the high affinity IgE receptor (FcεRI) signaling in mast cells. Studies with bone marrow-derived mast cells (BMMCs) from NTAL-/- mice indicated that NTAL is a negative regulator of FcεRI signa...
ORGANISM(S): Mus musculus 
2014-08-26 | GSE40731 | GEO
Expression data from activated and non-activated NTAL knockout, wild type and knockdown bone marrow derived mast cells
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