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MetabolomicsThe telomere-to-telomere (T2T) genome of Peucedanum praeruptorum Dunn provides insights into the genome evolution and coumarin biosynthesis

BACKGROUND: Traditional Chinese medicine has used Peucedanum praeruptorum Dunn (Apiaceae) for a long time. Various coumarins, including the significant root constituents Praeruptorin (A-E), are the active constituents of the dried roots of P. praeruptorum. Previous trans...

2024-04-02 | MTBLS8679 | MetaboLights
ProteomicsIdentification of evolutionarily conserved nuclear matrix proteins and their prokaryotic origins
Compared to prokaryotic cells, a typical eukaryotic cell is much more complex along with its endomembrane system and membrane-bound organelles. Although the endosymbiosis theories convincingly explain the evolution of membrane-bound organelles such as mitochondria and chloroplasts, very little is un...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Drosophila melanogaster (Fruit fly) 
2021-01-26 | PXD012926 | Pride
Core nuclear matrix proteome Nuclear evolution Nuclear matrix Nucleoskeleton Nuclear architecture 
TranscriptomicsThe insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome: DamID
Specific interactions of the genome with the nuclear lamina (NL) are thought to assist chromosome folding inside the nucleus and to contribute to the regulation of gene expression. High-resolution mapping has recently identified hundreds of large, sharply defined lamina-associated domains (LADs) in ...
ORGANISM(S): Drosophila melanogaster 
2011-01-24 | E-GEOD-20311 | biostudies-arrayexpress
UnknownPredicting structural material degradation in advanced nuclear reactors with ion irradiation.
Not available
S-EPMC7859217 | biostudies-literature
UnknownThe Small Nuclear Genomes of Selaginella Are Associated with a Low Rate of Genome Size Evolution.
Not available
S-EPMC4898805 | biostudies-literature
TranscriptomicsThe insulator protein SU(HW) modulates nuclear lamina interactions of the Drosophila genome: expression
Specific interactions of the genome with the nuclear lamina (NL) are thought to assist chromosome folding inside the nucleus and to contribute to the regulation of gene expression. High-resolution mapping has recently identified hundreds of large, sharply defined lamina-associated domains (LADs) in ...
ORGANISM(S): Drosophila melanogaster 
2011-01-24 | E-GEOD-20312 | biostudies-arrayexpress
UnknownEvolution: functional evolution of nuclear structure.
Not available
S-EPMC3198171 | biostudies-literature
ProteomicsA phylogenetic and proteomic reconstruction of eukaryotic chromatin evolution
Histones and associated chromatin proteins have essential functions in eukaryotic genome organization and regulation. Despite this fundamental role in eukaryotic cell biology, we lack a phylogenetically-comprehensive understanding of chromatin evolution. Here, we combine comparative proteomics and g...
ORGANISM(S): Acanthamoeba castellanii Sycon ciliatum Phytophthora infestans Thecamonas trahens Dictyostelium discoideum (Slime mold) Chlamydomonas reinhardtii Physcomitrella Nitrososphaera viennensis Bigelowiella natans Homo sapiens (Human) Methanobrevibacter cuticularis Gefionella okellyi Corallochytrium limacisporum Guillardia theta Naegleria gruberi Capsaspora owczarzaki Emiliania huxleyi Spizellomyces punctatus Methanospirillum stamsii Thalassiosira pseudonana Fabomonas tropica 
2022-08-12 | PXD031991 | Pride
Proteogenomics Histones Evolution Chromatin 
ProteomicsOrigin and evolution of neural microexons
The mechanisms by which entire programs of gene regulation emerged during evolution are poorly understood. Neuronal microexons represent the most conserved class of alternative splicing in vertebrates and are critical for proper brain development and function. Here, we discover neural microexon prog...
ORGANISM(S): Homo sapiens (Human) 
2019-03-12 | PXD010034 | Pride
Nuclear extract Microexon Human Ribonucleoprotein complex 
TranscriptomicsPatterns of gene expression and evolution in the human developing cerebral cortex
The cerebral cortex underwent a rapid expansion and complexification during recent primate evolution, but the underlying developmental mechanisms remain essentially unknown. In order to uncover genetic networks underlying the development of the human cerebral cortex, we profiled the transcriptome o...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-21858 | biostudies-arrayexpress
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