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ProteomicsNuclear pore complexes interactome dissection
We purified the different types of NPCs in yeast using a differential affinity purification strategy and analyzed their respective compositions and interactomes by mass spectrometry. Therefore, we compared the relative abundancies of specific nuclear factors and NPCs associated factor between all po...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2022-10-13 | PXD027872 | Pride
Nuclear pore heterogeneity Affinity purification Mrna maturation 
ProteomicsDocking a flexible basket onto the core of the nuclear pore complex
The nuclear basket attaches to the nucleoplasmic side of the nuclear pore complex (NPC), coupling transcription to mRNA quality control and export. The basket expands the functional repertoire of a subset of NPCs in S. cerevisiae by drawing a unique RNA/protein interactome. Yet, how the basket docks...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-07-11 | PXD052015 | Pride
Nup153 Nuclear pore complex Mlp2 Nuclear basket Mlp1 Membrane-based reconstitution Y-complex Alphafold screen. Nuclear envelope Slim Nucleocytoplasmic transport Npc assembly Tpr Nup85 Nup60 
UnknownA statistical image analysis framework for pore-free islands derived from heterogeneity distribution of nuclear pore complexes.
Not available
S-EPMC5701208 | biostudies-literature
UnknownThe Nuclear Pore Complex as a Flexible and Dynamic Gate.
Not available
S-EPMC4788809 | biostudies-literature
UnknownNup133 Is Required for Proper Nuclear Pore Basket Assembly and Dynamics in Embryonic Stem Cells.
Not available
S-EPMC5995580 | biostudies-literature
UnknownIntegrative spatiotemporal modeling of biomolecular processes: Application to the assembly of the nuclear pore complex.
Not available
S-EPMC11929490 | biostudies-literature
UnknownNuclear mRNA metabolism drives selective basket assembly on a subset of nuclear pore complexes in budding yeast.
Not available
S-EPMC10300651 | biostudies-literature
UnknownDocking a flexible basket onto the core of the nuclear pore complex.
Not available
S-EPMC11392808 | biostudies-literature
UnknownPhysical modeling of multivalent interactions in the nuclear pore complex.
Not available
S-EPMC8204217 | biostudies-literature
TranscriptomicsCharacterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer
We performed whole transcriptome sequencing of human monocytes that were co-cultured with estrogen receptor positive (ER+) or triple-negative (TNBC) breast cancer cell lines and studied the biological responses related to the differential gene activation in both cell types to understand how differen...
ORGANISM(S): Homo sapiens 
2015-11-19 | E-GEOD-75130 | biostudies-arrayexpress
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