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MetabolomicsMetabolome and proteome changes in skeletal muscle and blood of pre-weaning calves fed leucine and threonine supplemented diets

In pre-weaning calves, both leucine and threonine play important roles in growth and muscle metabolism. In this study, metabolomics, proteomics and clinical chemistry were used to assess the effects of leucine and threonine supplementation added to milk replacer on 14 newborn Holstein male calves...

2020-02-20 | MTBLS1045 | MetaboLights
ProteomicsLC-MS Based Draft Map of the Arabidopsis thaliana Nuclear Proteome and Protein Import in Pattern Triggered Immunity
An LC-MS based discovery proteomics approach was used to measure the nuclear proteome fractions of Arabidopsis thaliana cell culture. An enrichment score based on the relative abundance of cytoplasmic, mitochondrial and golgi markers in the nuclear protein fraction allowed us to curate the nuclear p...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-11-08 | PXD024349 | Pride
Arabidopsis thaliana  nucleus  nuclear proteome  stress response  flg22  nlp20 
ProteomicsComparative membrane proteomics reveals diverse cell regulators concentrated at the nuclear envelope
The nuclear envelope (NE) is a subdomain of the ER with a distinctive protein composition that underpins its role in nuclear compartmentalization. To expand an understanding of NE functions, we refined methods to reveal low abundance transmembrane (TM) proteins concentrated at the NE. De facto, th...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2023-01-25 | MSV000091154 | MassIVE
ProteomicsProteomic and bioinformatic analysis of the nuclear intrinsically disordered proteome
Intrinsically disordered proteins (IDPs) are biologically active molecules which are involved in many cellular functions although they do not possess a defined three-dimensional structure. They are mostly signalling and regulatory proteins. This study is the first large-scale proteomic analysis of t...
ORGANISM(S): Homo sapiens (Human) 
2015-09-21 | PXD002676 | Pride
Nuclear proteome Subproteome Transcription factors Intrinsically disordered proteins 
UnknownNuclear proteome response to cell wall removal in rice (Oryza sativa).
Not available
S-EPMC3695858 | biostudies-literature
UnknownTowards defining the nuclear proteome.
Not available
S-EPMC2395251 | biostudies-literature
ProteomicsIdentification of evolutionarily conserved nuclear matrix proteins and their prokaryotic origins
Compared to prokaryotic cells, a typical eukaryotic cell is much more complex along with its endomembrane system and membrane-bound organelles. Although the endosymbiosis theories convincingly explain the evolution of membrane-bound organelles such as mitochondria and chloroplasts, very little is un...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) Drosophila melanogaster (Fruit fly) 
2021-01-26 | PXD012926 | Pride
Core nuclear matrix proteome Nuclear evolution Nuclear matrix Nucleoskeleton Nuclear architecture 
ProteomicsThe nuclear proteome of Trypanosoma brucei
Trypanosoma brucei is a protozoan flagellate that is transmitted by tsetse flies into the mammalian bloodstream. The parasite has a huge impact on human health both directly by causing African sleeping sickness and indirectly, by infecting domestic cattle. The biology of trypanosomes involves some h...
ORGANISM(S): Trypanosoma brucei 
2017-07-31 | PXD006745 | Pride
Trypanosomes Nuclear 
ProteomicsNuclear-capture of endosomes drives depletion of nuclear G-actin to promote SRF/MRTF gene expression and cancer cell invasiveness (part 2: Surface and Nuclear Proteomes)
Signals are relayed from receptor tyrosine kinases (RTKs) at the cell surface to effector systems in the cytoplasm and nucleus, and coordination of this process is important for the execution of migratory phenotypes, such as cell scattering and invasion. The endosomal system influences how RTK sign...
ORGANISM(S): Homo sapiens (Human) 
2021-09-28 | PXD027268 | Pride
Invasiveness Serum-response factor (srf) Cell:cell repulsion Epha2 Heptocyte growth factor (hgf) Rab17 Surface and nuclear proteome Actin polymerisation Myocardin-related transcription factor (mrtf) Nuclear g-actin Nuclear import Pancreatic adenocarcinoma (pdac) 
ProteomicsMapping the micro-proteome of the nuclear lamina and lamin associated domains
The nuclear lamina is a proteinaceous network of filaments that provide both structural and gene regulatory functions by tethering proteins and large domains of DNA, so-called lamin associated domains (LADs), to the periphery of the nucleus. LADs are a large fraction of the mammalian genome that are...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-09 | PXD012943 | Pride
Lad Bioid Nuclear lamin Interactome Biosite 
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