Sort   by:  
 Page size 
Condensates induced by transcription inhibition mislocalizes active chromatin to nucleoli
hnRNP UL1 plays an important function in cell nuclei, where it is recruited to DNA damage sites and is involved in the repair of DNA double strand breaks. Furthermore, this protein is known as a transcriptional repressor of RNA polymerase II genes. In the present study, we have shown that hnRNP UL1 ...
ORGANISM(S): Homo sapiens (Human) 
2022-10-15 | PXD033233 | Pride
Neutrophil nucleolar stress rapidly releases nucleoli-stored IFNα during infection
The novel role of hnRNP UL1 in human cell nucleoli
The proper function of the genome relies on spatial organization of DNA, RNA, and proteins, but how transcription contributes to the organization is unclear. Here, we show that condensates induced by transcription inhibition (CITIs) drastically alter genome spatial organization. CITIs are formed by ...
ORGANISM(S): Homo sapiens 
2022-06-02 | GSE166623 | GEO
Sort   by:  
 Page size