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UnknownA nuclear protein quality control system for elimination of nucleolus-related inclusions.
Not available
S-EPMC11791210 | biostudies-literature
ProteomicsSILAC proteomics on MG132-induced nuclear aggregates
H1299 cells were labelled either with light (Lys0/Arg0) or heavy (Lys8/Arg10) amino acids and were either unstressed (light), stressed (heavy) with MG132 (15hrs) or stressed with MG132 and allowed to recover for 8hrs (light). Equal number of unstressed and MG132 stressed cells or MG132 stressed cell...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054637 | Pride
Nucleolus Nuclear inclusions Silac Proteasome Mg132 
UnknownA nuclear protein quality control system for elimination of nucleolus-related inclusions
Not available
S-SCDT-10_1038-S44318-024-00333-9 | biostudies-other
ProteomicsProteome-wide identification of NEDD8 modification sites reveals distinct proteomes for canonical and atypical NEDDylation
The Ubiquitin-like molecule NEDD8 controls several biological processes and is a promising target for therapeutic intervention. NEDDylation occurs through specific NEDD8 enzymes (canonical) or enzymes of the Ubiquitin system (atypical). Identification of NEDD8 sites on substrates is critical for del...
ORGANISM(S): Homo sapiens (Human) 
2021-02-10 | PXD022812 | Pride
Proteomics Sumo-2 Nucleolus-related inclusions Digly remnants Nedd8 Nedd8 polymers 
ProteomicsMulti-omics analysis using antibody-based in situ biotinylation technique reveals the mechanism of Cajal body formation
Membrane-less subcellular compartments such as cytoplasmic bodies, nuclear bodies, and paraspeckles play important roles in a variety of cellular functions. Although many of the techniques for identifying the components of cellular bodies were developed to address their function, no technique to com...
ORGANISM(S): Homo Sapiens (human) 
2024-07-06 | PXD043574 | JPOST Repository
ProteomicsMulti-omics analysis using antibody-based in situ biotinylation technique reveals the mechanism of Cajal body formation
Membrane-less subcellular compartments such as cytoplasmic bodies, nuclear bodies, and paraspeckles play important roles in a variety of cellular functions. Although many of the techniques for identifying the components of cellular bodies were developed to address their function, no technique to com...
ORGANISM(S): Homo Sapiens (human) 
2025-04-30 | PXD051888 | JPOST Repository
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