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Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target tissues. There are an estimated 150 million affected individuals worldwide, of whom a large proportion remains undiagnosed because of a lack of specific symptoms early in ...
2012-02-14 | MTBLS1 | MetaboLights
Data from the VLA lyssavirus genotyping microarray. The array platform for this data is GEO accession GPL8066, and consists of 624 oligos representing two viral families. The data set itself consists of 14 arrays, 7 hybridised with RNA from mice brains infected with 7 genotypes of lyssaviruses, 1 hy...
ORGANISM(S): Australian bat lyssavirus 
In the present study, we applied microarray technology to define a biosignature from the whole genome expression in lung and spleen samples after BCG vaccination and M. bovis infection of BALB/c mice. The aims were two-fold, namely to define biosignatures that could predict vaccine success before ch...
ORGANISM(S): Mus musculus 
We analyzed cerebral cortices (CTX) and midbrains (MB) from male C57BL/6J mice subjected to a CIE, 2BC paradigm, which induces heavy drinking and represents one of the best available animal models for alcohol dependence and relapse drinking. Samples from CTX and MB of 21 mice: 7 Naïve, 7 Air-2BC, an...
ORGANISM(S): Mus musculus 
Genome sequencing of Mycobacterium tuberculosis complex members has accelerated the search for new disease control tools. Antigen mining is one area that has benefited enormously from access to genome data. Here genes that were identified by transcriptome analysis as upregulated in response to an in...
ORGANISM(S): Mycobacterium tuberculosis 
G. sulfurreducens wild type and pilR mutant (GSU1495) were grown in chemostats for RNA extraction used for microarray analysis and qRT-PCR. The electron donor (acetate 5mM) was limiting at a dilution rate of 0.05 h-1 and ferric citrate(55mM) was used as the electron acceptor at 30C, as previously de...
ORGANISM(S): Geobacter sulfurreducens 
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