A metabolomic study of urinary changes in type 2 diabetes in human compared to the control group
Ontology highlight
ABSTRACT:
INSTRUMENT(S): Bruker
SUBMITTER: 
Jules Griffin Reza Salek
PROVIDER: MTBLS1 | MetaboLights | 2012-02-14
REPOSITORIES: MetaboLights
Dataset's files
primary
| Action | DRS | |||
|---|---|---|---|---|
| MTBLS1 | Other | |||
| ADG10003u_007.nmrML | Other | |||
| ADG10003u_007.zip | Other | |||
| ADG10003u_008.nmrML | Other | |||
| ADG10003u_008.zip | Other |
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Publications
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human.
Salek R M RM Maguire M L ML Bentley E E Rubtsov D V DV Hough T T Cheeseman M M Nunez D D Sweatman B C BC Haselden J N JN Cox R D RD Connor S C SC Griffin J L JL
Physiological genomics 20061226 2
Type 2 diabetes mellitus is the result of a combination of impaired insulin secretion with reduced insulin sensitivity of target tissues. There are an estimated 150 million affected individuals worldwide, of whom a large proportion remains undiagnosed because of a lack of specific symptoms early in this disorder and inadequate diagnostics. In this study, NMR-based metabolomic analysis in conjunction with multivariate statistics was applied to examine the urinary metabolic changes in two rodent m ...[more]
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