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ProteomicsNUPR1 inhibits hyperPARylation-associated cell death
Nuclear Protein 1 (NUPR1) is a nuclear intrinsically disordered protein of 82 amino acids that plays an important role in stress response and in cancer development. The project was aimed at identifying binding partners of NUPR1 in MiaPaCa-2 cells, in control and after stress condition: glucose starv...
ORGANISM(S): Homo sapiens (Human) 
2022-07-29 | PXD035236 | Pride
Lc-msms Pancreatic cancer Nupr1 Interactome 
TranscriptomicsIdentification of a mitochondrial defect gene signature reveals NUPR1 as a key regulator of liver cancer progression
Many cancer cells require more glycolytic adenosine triphosphate production due to a mitochondrial respiratory defect. However, the roles of mitochondrial defects in cancer development and progression remain unclear. To address the role of transcriptomic regulation by mitochondrial defects in liver ...
ORGANISM(S): Homo sapiens 
2015-12-16 | E-GEOD-64505 | biostudies-arrayexpress
TranscriptomicsNUPR1 a new target in liver cancer: implication in controlling cell growth, migration, invasion and sorafenib resistance
Sorafenib, an oral multikinase inhibitor, is the only approved agent for the treatment of advanced hepatocellular carcinoma (HCC). However, its benefits is modest, also because its mechanism of action remains elusive, therefore, a better understanding of its molecular action and molecular targets ar...
ORGANISM(S): Homo sapiens 
2016-06-15 | E-GEOD-73521 | biostudies-arrayexpress
TranscriptomicsThe chromatin protein Nupr1 regulates RelB-dependent NF-kB events necessary for pancreatic cancer development
The objective of this study was to elucidate the role of Nupr1 in pancreatic tumorigenesis. Using the Pdx-1-cre;LSL-KrasG12D mouse as model we discovered that, in contrast to KrasG12D pancreas that develop multiple foci of pancreatic intraepithelial neoplasia (PanIN), KrasG12D;Nupr1KO pancreas were ...
ORGANISM(S): Homo sapiens 
2012-02-01 | E-GEOD-35463 | biostudies-arrayexpress
GenomicsNegative regulation of endothelial to haematopoietic transition by Nupr1
Negative regulation of endothelial to haematopoietic transition by Nupr1
PRJNA846689 | ENA
GenomicsTranscriptional coregulator NUPR1 maintains tamoxifen resistance in breast cancer cells
Transcriptional coregulator NUPR1 maintains tamoxifen resistance in breast cancer cells
PRJNA408094 | ENA
GenomicsNupr1 controls the threshold of quiescent hematopoietic stem cells through p53 signaling pathway
Nupr1 controls the threshold of quiescent hematopoietic stem cells through p53 signaling pathway
PRJNA542594 | ENA
GenomicsTranscriptome of primary KP lung adenocarcinoma cells with Nupr1 knockout
Transcriptome of primary KP lung adenocarcinoma cells with Nupr1 knockout
PRJNA1160322 | ENA
GenomicsSingle Cell Analysis Reveals NUPR1 Promotes Docetaxel Resistance in Prostate Cancer
Single Cell Analysis Reveals NUPR1 Promotes Docetaxel Resistance in Prostate Cancer
PRJNA589746 | ENA
UnknownNUPR1 is a critical repressor of ferroptosis.
Not available
S-EPMC7843652 | biostudies-literature
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