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ProteomicsA novel nuclear RNA export pathway in the human testis – NXT2 is key player and azoospermia candidate gene
In eukaryotic cells, the nucleocytoplasmic export of bulk poly(A)+-mRNAs through the nuclear pore complex is mediated by the ubiquitously expressed NXT1-NXF1 heterodimer. In humans, autosomal NXT1 has an X-chromosomal paralogue called NXT2, which was subject to adaptive selection in primates and exh...
ORGANISM(S): Homo sapiens (Human) 
2025-03-05 | PXD061059 | Pride
Non-obstructive azoospermia Nxf3 Nxf2 Nuclear transport X chromosome Nuclear rna export Male infertility Nxt2 
ProteomicsA novel nuclear RNA export pathway in the human testis – NXT2 is key player and azoospermia candidate gene
In eukaryotic cells, the nucleocytoplasmic export of bulk poly(A)+-mRNAs through the nuclear pore complex is mediated by the ubiquitously expressed NXT1-NXF1 heterodimer. In humans, autosomal NXT1 has an X-chromosomal paralogue called NXT2, which was subject to adaptive selection in primates and exh...
ORGANISM(S): Homo sapiens (Human) 
2024-07-25 | PXD052904 | Pride
Non-obstructive azoospermia Nxf3 Nxf2 Nuclear transport X chromosome Nuclear rna export Male infertility Nxt2 
UnknownThe evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice.
Not available
S-EPMC5862965 | biostudies-literature
UnknownSelective Modulation of a Pan-Essential Protein as a Therapeutic Strategy in Cancer.
Not available
S-EPMC8419012 | biostudies-literature
UnknownDevelopment and Validation of Ten-RNA Binding Protein Signature Predicts Overall Survival in Osteosarcoma.
Not available
S-EPMC8671810 | biostudies-literature
UnknownTAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
Not available
S-EPMC86553 | biostudies-literature
UnknownDNA Methylation Profiles in Whole Blood of Huntington's Disease Patients.
Not available
S-EPMC6104454 | biostudies-literature
UnknownIdentification of an m6A Regulators-Mediated Prognosis Signature For Survival Prediction and Its Relevance to Immune Infiltration in Melanoma.
Not available
S-EPMC8656227 | biostudies-literature
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