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This model is from the article: Mechanistic explanations for counter-intuitive phosphorylation dynamics of the insulin receptor and insulin receptor substrate-1 in response to insulin in murine adipocytes. Nyman E, Fagerholm S, Jullesson D, Strålfors ...
2024-09-02 | BIOMD0000000423 | BioModels
Estrogen Receptor subtypes (ERα and ERβ) are transcription factors sharing similar structure, however, they often perform opposite roles in breast cancer’s cell proliferation and tumor progression. Besides the well-characterized genomic actions of ERs upon ligand binding, rapid non-genomic cytoplasm...
ORGANISM(S): Homo sapiens (Human) 
2015-03-11 | PXD001202 | Pride
This a model from the article: A Hierarchical Whole-body Modeling Approach Elucidates the Link between in Vitro Insulin Signaling and in Vivo Glucose Homeostasis. Nyman E, Brannmark C, Palmer R, Brugard J, Nystrom FH, Stralfors P, Cedersund G.J Biol Chem.2011 Jul 22;286(29)...
2024-09-02 | BIOMD0000000356 | BioModels
We have previously shown that IAV infection of human monocyte-derived macrophages causes major alterations to subcellular protein trafficking inside the cell and triggers robust protein secretion (Lietzén et al, 2011). Here, we have used high-throughput proteomics to identify proteins secreted in ex...
ORGANISM(S): Homo sapiens (Human) 
2017-02-07 | PXD004424 | Pride
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