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GenomicsRNA degradome analysis reveals substrates of NYN-domain containing DNE1 endoribonuclease in Arabidopsis
RNA degradome analysis reveals substrates of NYN-domain containing DNE1 endoribonuclease in Arabidopsis
PRJNA795486 | ENA
ProteomicsIdentification of proteins associated with the decapping complex and the endonuclease DNE1 in Arabidopsis
In this work, we used an unbiased approach coupling immunoprecipitations (IPs) and mass spectrometry to define the interactome of the decapping activator DCP1 and the decapping enzyme DCP2. In addition we unravel the interactome of the endonuclease DNE1 harboring an endoribonuclease domain of the NY...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2021-11-16 | PXD020780 | Pride
Dcp1 Mrna decapping Dne1 Rna degradation P-bodies Proteome Nyn domain Mass spectrometry 
TranscriptomicsEffect of Regnase-2/MCPIP2/ZC3H12B overexpression in human glioblastoma U-251 MG cell line.
Regnase-2/MCPIP2/ZC3H12B is a protein belonging to the ZC3H12 protein family. There are three other proteins of this family present in humans of which Regnase-1/MCPIP1/ZC3H12A is the founder member as well as the best-described protein. All proteins of this family contain a NYN domain with endoribon...
ORGANISM(S): Homo sapiens 
2024-01-24 | GSE248634 | GEO
UnknownOST-HTH: a novel predicted RNA-binding domain.
Not available
S-EPMC2848206 | biostudies-literature
TranscriptomicsRNA degradome analysis reveals substrates of NYN-domain containing DNE1 endoribonuclease in Arabidopsis
To gain insight into the functional role of DNE1 in cytoplasmic mRNA decay, we performed Parallel Analysis of RNA Ends (PARE) and Global Mapping of Uncapped and Cleaved Transcripts (GMUCT) analysis to identify DNE1-dependent cleavage sites based on their sensitivity to XRN4 within the Arabidopsis tr...
ORGANISM(S): Arabidopsis thaliana 
2023-04-25 | GSE193247 | GEO
UnknownRibonuclease activity of MARF1 controls oocyte RNA homeostasis and genome integrity in mice.
Not available
S-EPMC6217404 | biostudies-literature
UnknownHuman MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs.
Not available
S-EPMC6294520 | biostudies-literature
UnknownA minimal complex of KHNYN and zinc-finger antiviral protein binds and degrades single-stranded RNA.
Not available
S-EPMC11670115 | biostudies-literature
UnknownUse of chemical modification and mass spectrometry to identify substrate-contacting sites in proteinaceous RNase P, a tRNA processing enzyme.
Not available
S-EPMC4914120 | biostudies-literature
UnknownKHNYN is essential for the zinc finger antiviral protein (ZAP) to restrict HIV-1 containing clustered CpG dinucleotides.
Not available
S-EPMC6615859 | biostudies-literature
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