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P-bodies dynamics of hESCs by unveiling P-bodies properties of hESC and hESC-derived mesodermal cells
To identify RNAs accumulating in P-bodies (cytoslic RNP granules), P-bodies were purified from HEK293 cell extracts using a Flow Activated Particle Sorting (FAPS) method. Sorted P-bodies were compared to the pre-sorted fraction to identify RNA enriched in P-bodies.
ORGANISM(S): Homo sapiens 
RNA-Seq of purified P-bodies from HEK293 cells
RNA sequestration in P-bodies sustains myeloid leukemia [P-body-seq]
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, Udeshi ND, Mani DR,Carr SA, de Jager P, Myers CL, Lindquist S, Greenmyre TJ, Bartel DP, Feany MB, Sunyaev S, Chung CY and Khurana V. Alp...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-09 | MSV000089026 | MassIVE
RNA sequestration in P-bodies sustains myeloid leukaemia
RNA sequestration in P-bodies sustains myeloid leukaemia
Post-transcriptional regulation is pivotal in guiding the gene expression programs that instruct cell fate decisions. Recent studies emphasize the significance of biomolecular condensates in modulating gene expression through RNA processing and translational control. However, the functional roles of...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-07 | PXD058827 | Pride
The nucleation of RNP granules requires the participation of mRNAs, which simultaneously as becoming their target, dictate their properties. Here we report that in Arabidopsis the RNA helicase eIF4A limits the condensation of P-bodies acting as an RNA chaperone, disassembled from the eIF4F complex. ...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-03-25 | PXD061406 | Pride
Processing (P)-bodies are cytoplasmic membrane-less condensates including translationally repressed mRNAs and proteins involved in the mRNA decay machinery. The mechanisms underlying P-bodies nucleation and mRNA decay have been largely described. However, the impact of signaling networks in P-bodies...
ORGANISM(S): Homo sapiens 
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