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MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
Proteomics- Deep proteomics network and machine learning analysis of human cerebrospinal fluid in Japanese encephalitis virus infection
- Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus, and leading cause of neurological infection in Asia and the Pacific, with recent emergence in multiple territories in Australia in 2022. Patients may experience devastating socioeconomic consequences; JEV infection (JE) predominantl...
ORGANISM(S): Homo sapiens (Human) 
2023-06-08 | PXD034789 | Pride
Arbovirus - neurological infection Encephalitis Tmt Central nervous system infection Japanese encephalitis virus Flavivirus Lao pdr Brain infection Meningitis Cerebrospinal fluid (csf) 
TranscriptomicsResponse of peripheral blood mononuclear cells to west nile virus (E, NS2a) and type 1 diabetogenic antigens (GAD65, ZnT8) derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 3 healthy donors. The cells ...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72372 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells from 20 healthy donor and 15 patients with type 1 diabetes to type 1 diabetogenic protein (IGRP, PPI) derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 20 healthy donors and 15 pat...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72377 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells to influenza virus, human cytomegalovirus, and candida albicans derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 1 healthy donor. The cells w...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72371 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells from 15 healthy donor and 15 patients with type 1 diabetes to type 1 diabetogenic protein (GAD65, IGRP, PPI, ZnT8) and influenza virus M derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 15 healthy donors and 15 pat...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72376 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells from patients with allergy to cat and silver birch wood derived antigenic peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 2 donors with allergy. The c...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72373 | biostudies-arrayexpress
TranscriptomicsResponse of fresh or frozen peripheral blood mononuclear cells from 1 healthy donor to influenza virus derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 1 healthy donor. The fresh c...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72375 | biostudies-arrayexpress
TranscriptomicsResponse of peripheral blood mononuclear cells from young (≤ 45 years old) and old (>60 years old) healthy donors to influenza virus derived peptide stimulation.
CD4 T cell responses are characterized based on a limited number of molecular markers selected from exisiting knowledge. The goal of the experiment was to assess antigenic-peptide specific T-cell responses in vitro without bias using microarrays. PBMCs were isolated from 11 young (≤ 45 years old) ...
ORGANISM(S): Homo sapiens 
2016-08-15 | E-GEOD-72374 | biostudies-arrayexpress
UnknownExtracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors.
Not available
S-EPMC10962646 | biostudies-literature
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