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UnknownA single inactivating amino acid change in the SARS-CoV-2 NSP3 Mac1 domain attenuates viral replication in vivo.
Not available
S-EPMC10499221 | biostudies-literature
UnknownEpigenomic profiling reveals an association between persistence of DNA methylation and metabolic memory in the DCCT/EDIC type 1 diabetes cohort.
Not available
S-EPMC4890596 | biostudies-literature
ProteomicsResistance to ATR Inhibitors Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2
Over one million cases of gastric cancer are diagnosed each year and metastatic disease continues to have a poor prognosis. A significant proportion of gastric tumors have defects in the DNA damage response pathway creating therapeutic opportunities through synthetic lethal approaches. In particular...
ORGANISM(S): Homo sapiens (Human) 
2022-11-06 | PXD034887 | Pride
Upf2 Gastric cancer Ab Ph Nmd 
ProteomicsThe protein interaction landscape of breast cancer
Cancers have been associated with a diverse array of genomic alterations. To understand such alterations in breast invasive carcinoma at the level of cellular mechanisms, we have applied affinity-purification mass spectrometry to delineate comprehensive biophysical interaction networks for 40 freque...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD025931 | Pride
Breast cancer Ph Human Ub 
TranscriptomicsAnalysis of human neurotrophins and receptors in bone marrow stromal cells (BMSC) treated with NGF or BDNF
BMSC gene expression profiling was completed to examine the baseline neurotrophin and receptor gene expression in BMSC and to evaulate changes in gene expression in response to NGF or BDNF stimulation In the study, primary BMSC were treated with recombinant human NGF or BDNF for 24 hours. Following...
ORGANISM(S): Homo sapiens 
2010-05-01 | E-GEOD-18537 | biostudies-arrayexpress
UnknownConsensus coding sequence (CCDS) database: a standardized set of human and mouse protein-coding regions supported by expert curation.
Not available
S-EPMC5753299 | biostudies-literature
ProteomicsThe protein interaction landscape of breast cancer
Cancers have been associated with diverse sets of genomic alterations, many of which are rare with uncertain significance. To understand the cellular mechanisms impacted by such alterations in breast invasive carcinoma, we have applied affinity-purification mass spectrometry to delineate comprehensi...
ORGANISM(S): Homo sapiens (Human) 
2021-11-02 | PXD019639 | Pride
Brca1 Spinophilin Proteomics Protein-protein interaction network Akt Breast cancer 
UnknownResistance to ATR Inhibitors Is Mediated by Loss of the Nonsense-Mediated Decay Factor UPF2.
Not available
S-EPMC9633439 | biostudies-literature
UnknownThe long-term effects of type 1 diabetes treatment and complications on health-related quality of life: a 23-year follow-up of the Diabetes Control and Complications/Epidemiology of Diabetes Interventions and Complications cohort.
Not available
S-EPMC3781542 | biostudies-literature
UnknownA protein interaction landscape of breast cancer.
Not available
S-EPMC9040556 | biostudies-literature
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