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ProteomicsPhosphorylated RNAPII interactome via 4H8 antibody IP with OGG1 inhibitor
RNAPII pull down of chromatin associated proteins in the Flp-In T-REx HEK293 parental cell line. Phosphorylated RNAPII interactome was measured in six conditions; Untreated (with and without OGG1i), 1mM H2O2 treatment for 15minutes (with and without OGG1i) and 2 hours recovery following media washo...
ORGANISM(S): Homo sapiens (Human) 
2026-06-22 | PXD070086 | Pride
Ogg1i 4h8 Interactome Phosphorylated rnapii 
UnknownOGG1 competitive inhibitors show important off-target effects by directly inhibiting efflux pumps and disturbing mitotic progression.
Not available
S-EPMC9936318 | biostudies-literature
TranscriptomicsA3shNT cell transcriptomics
Altered oncogene expression in cancer cells causes loss of redox homeostasis resulting in oxidative DNA damage, e.g., 8-oxoguanine (8-oxoG), repaired by base excision repair (BER). PARP1 coordinates BER and relies on the upstream 8-oxoguanine-DNA glycosylase (OGG1) to recognise and excise 8-oxoG. He...
ORGANISM(S): Homo sapiens 
2020-08-07 | GSE155782 | GEO
UnknownTargeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Not available
S-EPMC7708037 | biostudies-literature
GenomicsA3shNT cell transcriptomics
A3shNT cell transcriptomics
PRJNA655614 | ENA
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