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Global regulation of spindle-associated proteins is crucial in oocytes due to the absence of centrosomes and their very large cytoplasmic volume, but little is known about how this is achieved beyond involvement of the Ran-importin pathway. We previously uncovered a novel regulatory mechanism in Dr...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2022-05-04 | PXD030445 | Pride
The meiotic spindle in oocytes is formed without centrosomes. How a bipolar spindle is assembled and maintained around chromosomes in oocytes remains to be established. Multiple kinases are known to regulate the meiotic spindle, but how they execute their function is poorly understood. We found t...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2017-08-29 | PXD006080 | Pride
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