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TranscriptomicsGene expression in astrocytes upon sustained GSK-3 inhibition by small molecule
In order to identify molecular targets that mediates the stimulation of astrocyte's migration upon sustained specific inhibition of GSK-3, we have employed whole genome microarray expression profiling. Murine cortical-striatal astrocytes grown in primary culture were treated in vitro for 48 h with e...
ORGANISM(S): Mus musculus 
2011-08-31 | E-GEOD-25770 | biostudies-arrayexpress
TranscriptomicsFunctional analysis of HOXD9 in human gliomas and glioma cancer stem cells
HOX genes encode a family of homeodomain-containing transcription factors involved in the determination of cell fate and identity during embryonic development. They also behave as oncogenes in some malignancies. In this study, we found high expression of the HOXD9 gene transcript in glioma cell line...
ORGANISM(S): Homo sapiens 
2011-04-16 | E-GEOD-28618 | biostudies-arrayexpress
TranscriptomicsRobust production of human neural cells by establishing neuroepithelial-like stem cells from peripheral blood mononuclear cell-derived feeder-free iPSCs under xeno-free conditions
We performed a microarray experiment to analyze the transcriptional profile of human fetal tissue derived neural stem/progenitor cells, human iPSCs, or human iPSC-derived neural stem/progenitor cells generated using xenogenic or xeno-free reagents. Gene expression patterns were compared among human ...
ORGANISM(S): Homo sapiens 
2016-08-22 | E-GEOD-76900 | biostudies-arrayexpress
TranscriptomicsPretreatment with Gamma-Secretase Inhibitor Prevents Tumor-Like Overgrowth in Human iPSC-Derived Transplant for Spinal Cord Injury
Cell cycle- and more mature neuronal marker-related genes increased by > 2-fold change in both the GSI groups compared to the control group. To analyze gene expression profiles in hiPSC-NS/PCs treated with or without Gamma-secretase inhibitor.
ORGANISM(S): Homo sapiens 
2016-01-06 | E-GEOD-76556 | biostudies-arrayexpress
ProteomicsProteomics of human tau-transgenic mice reveals protein modules associated with tau pathologies
Abnormally accumulated tau protein aggregates are one of the hallmarks of dementia, including Alzheimer’s disease (AD), and are believed to play a critical role in neurodegeneration. In order to investigate proteomic alteration driven by tau aggregates, we implemented quantitative proteomics to anal...
ORGANISM(S): Mus Musculus (mouse) 
PXD031129 | JPOST Repository
ProteomicsTime-resolved analysis of vUNG phosphorylation
Time-resolved phosphoproteomic analysis of HEp-2 cells infected with wild type HSV-1(F)
ORGANISM(S): Cellular Organisms 
PXD055199 | JPOST Repository
ProteomicsMS-based determination of vUNG phosphorylation
Phosphoproteomic analysis of HEp-2 cells infected with wild type HSV-1(F)
ORGANISM(S): Cellular Organisms 
PXD043453 | JPOST Repository
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