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TranscriptomicsCD133/CD140a-Based Isolation of Distinct Human Multipotent Neural Progenitor Cells and Oligodendrocyte Progenitor Cells
The mechanisms underlying the specification of oligodendrocyte fate from multipotent neural progenitor cells (NPCs) in developing human brain are unknown. In this study, we sought to identify antigens sufficient to distinguish NPCs free from oligodendrocyte progenitor cells (OPCs). We investigated t...
ORGANISM(S): Homo sapiens 
2013-04-23 | E-GEOD-40676 | biostudies-arrayexpress
TranscriptomicsCandidate pathways for promoting differentiation and quiescence of oligodendrocyte progenitor-like cells in glioblastoma
The mature CNS contains PDGFRA+ ‘oligodendrocyte progenitor cells’ (OPC) which may remain quiescent, proliferate, or differentiate into oligodendrocytes. In human gliomas, rapidly proliferating Olig2+ cells resembling OPCs are frequently observed. We sought to identify, in vivo, candidate pathways u...
ORGANISM(S): Mus musculus 
2012-10-04 | E-GEOD-30626 | biostudies-arrayexpress
ProteomicsOxygen and hormone effect on rat oligodrendrocyte progenitor cell line (OLN93)
Hyperoxia is known to cause cerebral white matter injury in preterm infants. Preterm birth is also associated with sudden hormonal changes which includes drop of estrogen level and increased postnatal production of fetal zone steroids (FZS). Therefore, we investigated the effect of hyperoxia (80...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-05-16 | PXD031878 | Pride
Oligodendrocyte progenitor cell line Hyperoxia Fetal zone steroids Lc-ms/ms 
TranscriptomicsRNA-seq analysis of single cells of the oligodendrocyte lineage from nine distinct regions of the anterior-posterior and dorsal-ventral axis of the mouse juvenile central nervous system
5069 transcriptomes of single oligodendrocyte cells from spinal cord, substantia nigra-ventral tegmental area, striatum, amygdala, hypothalamic nuclei, zona incerta, hippocampus, and somatosensory cortex of male and female mice between post-natal day 21 and 90. The study aimed at identifying diverse...
ORGANISM(S): Mus musculus 
2016-06-10 | E-GEOD-75330 | biostudies-arrayexpress
GenomicsmicroRNAs dysregulated in multiple sclerosis affect the differentiation of CG-4 cells, an oligodendrocyte progenitor cell line
microRNAs dysregulated in multiple sclerosis affect the differentiation of CG-4 cells, an oligodendrocyte progenitor cell line
PRJNA1023246 | ENA
GenomicsSingle-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor Cells
Single-Cell Transcriptomic Analysis Reveals Molecular Diversity of Human Oligodendrocyte Progenitor Cells
PRJNA610263 | ENA
UnknownNeural and oligodendrocyte progenitor cells: transferrin effects on cell proliferation.
Not available
S-EPMC3592559 | biostudies-literature
ProteomicsImpact of FGF-2 and FGF-2 containing cell culture supernatants on the intracellular protein composition of ReNcell derived neuron
FGF-2 is an important protein involved in a vast number of molecular pathways and a number of cellular functions including glial cell differentiation and response to axon injury. This protein was found to be present significantly in supernatants of female derived murine oligodendrocyte progenitor ce...
ORGANISM(S): Homo sapiens (Human) 
2025-09-29 | PXD060285 | Pride
Human neural progenitor cell line Rencell vm Opc cell culture supernatant Fgf-2 Secretome lc-ms/ms 
UnknownSelect neurotrophins promote oligodendrocyte progenitor cell process outgrowth in the presence of chondroitin sulfate proteoglycans.
Not available
S-EPMC7986866 | biostudies-literature
GenomicsCRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents
CRISPR-edited human ES-derived oligodendrocyte progenitor cells improve remyelination in rodents
PRJNA1008174 | ENA
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