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ProteomicsViral immune evasions differentially impact cell surface presentation of MHC I allomorphs already at the peptide-loading complex
The transporter associated with antigen processing (TAP) translocates peptides from the cytosol into the endoplasmic reticulum (ER) where they are loaded onto major histocompatibility class I (MHC I) molecules. Stable peptide-MHC I complexes travel to the cell surface and present their antigenic car...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027408 | Pride
Er quality control Major histocompatibility complex class i Mass spectrometry Mhc i biogenesis Viral immune evasion Peptide-loading complex 
ProteomicsMajor Proteomic Changes Associated with Amyloid Induced Biofilm Formation in Pseudomonas aeruginosa PAO1
The newly identified functional amyloids in Pseudomonas (Fap) are associated with increased aggregation and biofilm formation in the opportunistic pathogen P. aeruginosa. However, whether this phenomenon can be simply ascribed to the mechanical properties of the amyloid fibrils remains...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2014-10-17 | PXD001373 | Pride
Chronic infection Biofilms Cystic fibrosis Functional amyloids Pseudomonas aeruginosa pao1 Microbial proteomics 
ProteomicsSystematic evaluation and modulation of HLA class I downregulation in Merkel cell carcinoma
Lee PC, Klaeger S, Le PM, Korthauer K, Cheng J, Wong A, Tarren A, Lemvigh C, Sarkizova S, Li L, Frost TC, Nomburg J, Liu X, Pomerance L, Doherty L, Witten E, Zhang W, Apffel A, Wallace L, Neuberg D, Olsen L, Thakuria M, Clauser K, Starrett G, Doench J, Buhrlage SJ, Carr SA, DeCaprio JA, Wu CJ, Keski...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-20 | MSV000087251 | MassIVE
ProteomicsProteogenomic identification of Hepatitis B virus (HBV) genotype-specific HLA-I restricted peptides from HBV-positive patient liver tissues
The presentation of virus-derived peptides by HLA class I molecules on the surface of an infected cell and the recognition of these HLA-peptide complexes by, and subsequent activation of, CD8+ cytotoxic T cells provides an important mechanism for immune protection against viruses. Recent advances in...
ORGANISM(S): Homo sapiens (Human) 
2023-01-03 | PXD037270 | Pride
Proteogenomics Hepatocellular carcinoma Hepatitis b Human leukocyte antigen (hla) Immunopeptidomics 
TranscriptomicsTranscription profiling of human skin during elicitation of allergic contact dermatitis - time series
Genes involved in the inflammatory response resulting in allergic contact dermatitis (ACD) are only partly known. In this study, we introduce the use of high density oligonucleotide arrays for gene expression profiling in human skin during the elicitation of ACD. Skin biopsies from normal and nickel...
ORGANISM(S): Homo sapiens 
2008-06-14 | E-GEOD-6281 | biostudies-arrayexpress
UnknownClarifying Associations between Childhood Adversity, Social Support, Behavioral Factors, and Mental Health, Health, and Well-Being in Adulthood: A Population-Based Study.
Not available
S-EPMC4879780 | biostudies-literature
TranscriptomicsExpression quantitative trait loci (eQTL) analysis of Brassica rapa under varying soil phosphorus (P) supplies
The aim of this study was to identify eQTL in Brassica rapa grown under altered soil phosphorus (P) supply, to understand better the genetic architecture of P-use efficiency (PUE) in plants. Recombinant inbred lines (RILs) of the BraIRRI mapping population were grown at adequate and growth-limiting ...
ORGANISM(S): Brassica rapa 
2011-06-29 | E-GEOD-27052 | biostudies-arrayexpress
UnknownLeptotrichia species in human infections II.
Not available
S-EPMC5646626 | biostudies-literature
UnknownIn silico Comparison of 19 Porphyromonas gingivalis Strains in Genomics, Phylogenetics, Phylogenomics and Functional Genomics.
Not available
S-EPMC5306136 | biostudies-literature
TranscriptomicsGlobal gene expression analysis of Salmonella enterica serovar Enteritidis during growth in whole egg
Even though the incidence of salmonellosis in humans has decreased over the last years, Salmonella spp. are still a leading cause of foodborne outbreaks in Europe (Anon., 2014). Of more than 2500 different serovars of Salmonella enterica, S. enterica serovar Enteritidis (S. Enteritidis) is the most ...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Enteritidis 
2016-03-04 | E-MTAB-4521 | biostudies-arrayexpress
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