Oma1 - OmicsDI

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(S)-Menthone 8-thioacetate (1)

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Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (5)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne Germany (4)
Max-Planck-Institute for Biology of Ageing Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne, Germany (2)
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Department II of Internal Medicine and Center for Molecular Medicine Cologne, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany (1)
Department Langer - Mitochondrial Proteostasis Max-Planck Institut für Altersforschung Joseph-Stelzmann Str 9b 50931 Cologne, Germany (1)
Department of Animal Sciences, Purdue University, West Lafayette, IN 47907, USA Center for Cancer Research Purdue University, West Lafayette, IN 47907, USA (1)
Department of Mitochondrial Proteostasis Joseph-Stelzmann-Str. 9b 50931 Cologne (1)
Head of Proteomics, Dept of Immunology, University of Oslo and Oslo University Hospital (1)
Institute for Genetics, Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), and University of Cologne, Cologne, Germany (1)
Max-Planck-Institute for Biology of Ageing Joseph-Stelzmann-Str. 9b 50931 Cologne, Germany (1)
Universität Greifswald Institut für Pharmazie, AG Pharmazeutische Biotechnologie Greifswald, Germany (1)

Tags

xref:PubMed:39379554 (6)
xref:PubMed:36113464 (1)
xref:PubMed:29593106 (1)
xref:PubMed:32132707 (1)
xref:PubMed:37832546 (1)
xref:PubMed:22433842 (1)
xref:PubMed:41760807 (1)

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The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage

The metabolic plasticity of mitochondria supports cell development and differentiation and ensures cell survival under stress. The peptidase OMA1 regulates mitochondrial morphology and stress signaling and orchestrates tumorigenesis and cell fate decisions in a cell and tissue-specific manner. Here,...

ORGANISM(S): Mus musculus (Mouse)

2023-04-04 | PXD036595 | Pride

Neo N termiome of Oma1 and WT knockout HeLa cells

To understand how OMA1 affects mitochondrial proteostasis and stress responses, we performed a proteomic survey of OMA1-deficient cells for proteolytic substrates. We demonstrate that OMA1 cleaves the mitochondrial chaperone DNAJC15 facilitating its degradation by the mitochondrial m-AAA protease. T...

ORGANISM(S): Homo sapiens (Human)

2025-12-19 | PXD061134 | Pride

Neon Hela Oma1

Expression data from diet-induced obesity Oma1-deficient mice.

Transriptional profiling of white adipose tissue extracted from obese mice. White adipose tissues were extrated from Oma1-deficient mouse and control after 20 weeks of diet-induced obesity. RNA were extracted and hybridated with Mouse Gene 1.0 ST from Affymetrix microarrays.

ORGANISM(S): Mus musculus

2012-01-01 | E-GEOD-27525 | biostudies-arrayexpress

Effects of acute OMA1 knockdown on global gene expression in CHCHD10 G58R mutants

PRJNA782888 | ENA

EMBOJ-2024-119185R-Q OMA1 protects from liver injury

ORGANISM(S): Mus musculus (Mouse)

2026-06-02 | PXD058566 | Pride

Proteomics differential expression Oma1

OMA1-An integral membrane protease?

Not available

S-EPMC7770061 | biostudies-literature

Expression data from adult C10 G58R OMA1 KD mouse liver.