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ProteomicsSimple and efficient micro-SPE tip-based sample preparation workflow to enable sensitive proteomic profiling of limited samples
In-depth LC-MS-based proteomic profiling of limited samples has been problematic due, in large part, to the inefficiency of sample preparation and attendant sample losses. To address this issue, we developed On-Micro Solid-phase Extraction Tip-based (OmSET) sample preparation for limited biological...
ORGANISM(S): Homo sapiens (Human) 
2021-02-23 | PXD022313 | Pride
Micro-spe tip Omset Limited sample On-micro solid-phase extraction tip Sample preparation Stagetip 
UnknownSimple and Efficient Microsolid-Phase Extraction Tip-Based Sample Preparation Workflow to Enable Sensitive Proteomic Profiling of Limited Samples (200 to 10,000 Cells).
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S-EPMC7954648 | biostudies-literature
ProteomicsU87 Glioblastoma Cell-Derived Extracellular Vesicles Reflect 2D vs. 3D Culture Adaptations and Temozolomide Response
Glioblastoma (GBM) is an aggressive brain tumor marked by extensive heterogeneity, resistance to therapy, and dismal prognosis. Extracellular vesicles (EVs) have emerged as key players in GBM biology, mediating intercellular communication and therapy adaptation. However, the exact functions, signifi...
ORGANISM(S): Homo sapiens (Human) 
2026-08-15 | PXD069801 | Pride
Cancer Mass spectrometry Glioblastoma Extracellular vesicles U87 
ProteomicsMultimode Chromatography-based Techniques for High Purity Isolation of Extracellular Vesicles from Human Blood Plasma
Extracellular vesicles (EVs) play a pivotal role in various biological pathways, such as immune responses and the progression of diseases, including cancer. However, it is challenging to isolate EVs at high purity from blood plasma and other biofluids due to their low abundance compared to more pred...
ORGANISM(S): Homo sapiens (Human) 
2025-08-04 | PXD043956 | Pride
Size exclusion chromatography Mass spectrometry Multimode chromatography Plasma Extracellular vesicles 
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