Oncogenes - OmicsDI

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Unknown (5684)
Genomics (1967)
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Genomic (7)
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Organisms

Homo sapiens (1682)
Mus musculus (531)
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Danio rerio (14)
Drosophila melanogaster (8)
synthetic construct (8)
Canis lupus familiaris (4)
Macaca mulatta (3)
Arabidopsis thaliana (3)
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Human gammaherpesvirus 8 (2)
Acomys cahirinus (2)
Mus (2)
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human papillomavirus 18 (1)
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Merkel cell polyomavirus (1)
Macacine alphaherpesvirus 1 (1)
Betapolyomavirus hominis (1)
Human alphaherpesvirus 2 (1)
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Human betaherpesvirus 6B (1)
human gammaherpesvirus 4 (1)

Organisms

Homo sapiens (912)
Mus musculus (275)
Danio rerio (8)
Rattus norvegicus (6)
Canis lupus familiaris (4)
Drosophila melanogaster (3)
Mus (2)
unidentified (2)
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Dasypus novemcinctus (1)
Heterocephalus glaber (1)
Cricetulus griseus (1)
Juglans regia (1)
Xenopus tropicalis (1)
synthetic construct (1)
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Mus musculus musculus (1)
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Repository

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geo (1161)
biostudies-arrayexpress (906)
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pride (92)
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EVA (1)

Tissue

Cell culture (39)
Epithelial cell (13)
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Brain (4)
Liver (4)
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Kidney (3)
Lung (3)
Stomach (3)
Blood cell (2)
Blood plasma (2)
Early embryonic cell (2)
Egg (2)
Malignant cell (2)
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Disease

Breast cancer (11)
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Ovarian cancer (2)
Multiple myeloma (2)
Osteosarcoma (2)
Early stage liver carcinogenesis (1)
Integrated HPV16 only (1)
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Normal renal cortex (1)
Wounded; tumour (1)
Senescence induced (1)
Non-Hodgkin lymphoma (1)
Lymphoma (1)
Leukemic (1)
Neuroblastoma-undifferentiated (1)
Imatinib-resistant CML cell line subclone (1)
Myelolipoma (1)
Glioma (1)
Colorectal carcinoma (1)
Colon adenocarcinoma (1)
Bladder transitional carcinoma (1)
Midgut carcinoid liver metastasis (1)
Chronic myelogenous leukemia (1)
Cancer (1)
S enteritidis (1)

Technology Type

Mass Spectrometry (92)
Shotgun proteomics (45)
Affinity purification coupled with mass spectrometry proteomics (16)
Bottom-up proteomics (11)
Gel-based experiment (11)
Illumina HiSeq 2000 (10)
Data-dependent acquisition (9)
Mass spectrometry (7)
Data-independent acquisition (6)
Illumina HiSeq 2500, ILLUMINA (5)
Mass spectrometry assay (5)
Illumina HiSeq 2500 (4)
ILLUMINA, Illumina HiSeq 2000 (3)
SWATH MS (3)
Illumina HiSeq 2000, ILLUMINA (2)
RNA mass spectrometry (2)
ILLUMINA, Illumina HiSeq 1000 (1)
Illumina HiSeq 2000, PacBio RS II (1)
Illumina MiSeq, ILLUMINA (1)
Illumina HiScanSQ, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, HiSeq X Ten (1)
Illumina HiSeq 4000, ILLUMINA (1)
Illumina HumanMethylation 450K (1)
CYTOSCANHD, ILLUMINA, HUMANOMNI1QUAD, HUMANOMNIEXPRESS, Affymetrix HG_U133_+2, Illumina HiSeq 2000 (1)
Illumina HiSeq 2500, Illumina MiSeq, NextSeq 500, Illumina HiSeq 2000 (1)
Illumina 2.5M, Illumina HiSeq 2000 (1)
AB SOLiD System 3.0 (1)
Illumina MiSeq (1)
Illumina Genome Analyzer II (1)
NMR spectroscopy (1)

Instrument Platform

NextSeq 500 (17)
Illumina HiSeq 2500 (11)
LTQ Orbitrap Velos (11)
Illumina NovaSeq 6000 (9)
Illumina HiSeq 4000 (7)
Illumina HiSeq 2000 (5)
Orbitrap Fusion Lumos (4)
Q Exactive (4)
ScanArray 4000XL [PerkinElmer] (2)
Scanning hardware (2)
Illumina NovaSeq X (2)
Ion Torrent PGM (2)
DNBSEQ-G400 (2)
HiSeq X Ten (2)
LTQ Orbitrap (2)
Orbitrap Exploris 480 (2)
Orbitrap Fusion (2)
Genolab M (1)
G2565BA DNA microarray scanner (1)
BD Fortessa (1)
ViiA 7 Real-Time PCR System (Life Technologies) (1)
Agfa 1236s (1)
Gene Titan (1)
Other (1)
Illumina Genome Analyzer IIx (1)
GenePix 4000B [Axon Instruments] (1)
NextSeq 2000 (1)
Illumina MiSeq (1)
NextSeq 550 (1)
- (1)

Publication Date

2013 (197)
2025 (151)
2015 (138)
2010 (138)
2024 (135)
2012 (124)
2014 (119)
2011 (115)
2026 (113)
2022 (112)
2016 (105)
2008 (104)
2023 (102)
2019 (97)
2009 (94)
2021 (86)
2018 (77)
2020 (67)
2017 (59)
2007 (43)
2005 (18)
2006 (10)
2004 (5)
2003 (3)

UNIPROT ID/AC

Q91854 (1)
A4F2Q1 (1)
O00512 (1)
O60264 (1)
P45481 (1)
Q9V9W8 (1)
Q92837 (1)
Q8UVT6 (1)
P67870 (1)
P68400 (1)
P54367 (1)
P18537 (1)
P51452 (1)
P20936 (1)
P60953 (1)
P24394 (1)
O75197 (1)
O75581 (1)
Q07889 (1)
P35222 (1)
P49841 (1)
P28482 (1)
Q02750 (1)
P04049 (1)
P01116 (1)
P56704 (1)
P29353 (1)
P00533 (1)
P62993 (1)
P01133 (1)

CHEBI ID

CHEBI:17234 (4)
CHEBI:28757 (3)
CHEBI:16610 (3)
CHEBI:17754 (3)
CHEBI:60645 (3)
CHEBI:16668 (3)
CHEBI:16113 (3)
CHEBI:15428 (3)
CHEBI:15356 (3)
CHEBI:24898 (3)
CHEBI:15891 (3)
CHEBI:18012 (3)
CHEBI:32816 (3)
CHEBI:78320 (3)
CHEBI:30915 (3)
CHEBI:16027 (3)
CHEBI:16708 (3)
CHEBI:17568 (3)
CHEBI:15741 (3)
CHEBI:17268 (3)
CHEBI:16199 (3)
CHEBI:15756 (3)
CHEBI:30769 (3)
CHEBI:11805 (2)
CHEBI:48929 (2)
CHEBI:68465 (2)
CHEBI:176456 (2)
CHEBI:25750 (1)
CHEBI:15422 (1)
CHEBI:16761 (1)

Metabolite Name

Cholesterol (3)
Urea (3)
Fructose (3)
Cysteine (3)
Adenine (3)
Spermidine (3)
Uracil (3)
Taurine (3)
Myo-inositol (3)
Hypotaurine (3)
Glycine (3)
Glycerol (3)
Glucose (3)
Cysteinylglycine disulfide* (2)
Prolylhydroxyproline (2)
Dihomolinoleate (20:2n6) (2)
2-palmitoleoyl-GPC* (16:1)* (2)
1-palmitoyl-GPI* (16:0) (2)
1-linoleoyl-GPI* (18:2)* (2)
1-arachidonoyl-GPI* (20:4)* (2)
Propionylcarnitine (C3) (2)
Tartarate (2)
2,6-dihydroxybenzoic acid (2)
Ascorbic acid 3-sulfate* (2)
3-amino-2-piperidone (2)
3-formylindole (2)
3-hydroxyoleoylcarnitine (2)
3-hydroxypalmitoylcarnitine (2)
Ascorbic acid 2-sulfate (2)
1-linoleoyl-2-arachidonoyl-GPC (18:2/20:4n6)* (2)

First Public Date

2014 (250)
2025 (151)
2024 (150)
2026 (115)
2023 (105)
2022 (100)
2019 (96)
2021 (79)
2018 (78)
2015 (70)
2020 (66)
2017 (61)
2013 (46)
2016 (41)
2012 (2)

Modelling Approach

Ordinary differential equation model (3)

Study status

Not provided (2)
Terminated (1)

Lab affiliation

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA (6)
1. Department of Biochemistry and Molecular Cell Biology, State Key Laboratory of Oncogenes and Related Genes, Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine. (2)
Division of Gastroenterology and Hepatology; Shanghai Institute of Digestive Disease; NHC Key Laboratory of Digestive Diseases; State Key Laboratory for Oncogenes and Related Genes; Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200001, China (2)
Monash University (2)
Protim Irset Inserm U1085 (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
1 Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China. 2 Center of Clinical Oncology, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China. 3 State Key Laboratory Jiangsu Center for the Collaboration and Innovation of Cancer Biotherapy, Cancer Institute, Xuzhou Medical University, Xuzhou, Jiangsu, China. (1)
1 Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2 Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA 3 Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA 4 Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA (1)
1Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China. 2Institute of Health Sciences, Shanghai Institutes for Biological Sciences of Chinese Academy of Sciences and SJTU-SM, Shanghai 200025, China. (1)
1Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 2Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, NC 27599, USA. 3Biological and Biomedical Sciences Program, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. (1)
Anonymity for double-blind review (1)
Associate Professor Regional Centre for Biotechnology (1)
Biomedical Research in Melanoma-Animal Models and Cancer Laboratory Vall d'Hebron Research Institute (VHIR), Vall d'Hebron Hospital Barcelona-UAB Barcelona, 08035, Spain. (1)
Cancer Biology Department, Fox Chase Cancer Center, Philadelphia, PA, USA (1)
Cancer Biology, Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States (1)
Cancer Genetics Group Josep Carreras Leukaemia Research Institute Can Ruti Campus Ctra de Can Ruti, Camí de les Escoles s/n 08916 Badalona, Barcelona Spain (1)
Cancer Research UK Manchester Institute (1)
Cancer Science Institute of Singapore, National University of Singapore (1)
Cancer Science Institute of Singapore, National University of Singapore, Singapore (1)
CeMM, Research Center for Molecular Medicine, Austrian Academy of Sciences, Austria (1)
Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University, 3584 CG Utrecht, The Netherlands. (1)
Centre de Recherche en Cancérologie et Immunologie Nantes Angers (CRCINA), INSERM U1232, Paul Papin ICO Cancer Center, Université d’Angers, France. (1)
Chemical Proteomics core facility Department of Medical Biochemistry and Biophysics (MBB) Karolinska Institutet, Sweden (1)
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates. (1)
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, (1)
Department of Chemistry, Princeton University (1)
Department of Clinical Laboratory, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, China. (1)
Department of Dermatology, Stanford School of Medicine, Stanford University (1)
Department of Integrated Immunobiology Duke School of Medicine Durham, NC, USA (1)
Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, Sahlgrenska Academy, Gothenburg University, Sweden. (1)

Keyword

Immunohistochemistry, (1)
Monoclonal antibodies, (1)
Predictive model, (1)
Antiangiogenic agents, (1)
Medical imaging (1)
Colorectal cancer with liver metastases (1)
MSI, TS, Colorectal Cancer, DM. (1)
Colorectal cancer, (1)
Bevacizumab (1)
Cetuximab (1)

IsPrivate

False (3)

Modification

2x(15)N labeled L-lysine (1)
4x(15)N labeled L-arginine (1)

Study type

Transcription profiling by array (543)
RNA-seq of coding RNA (89)
Comparative genomic hybridization by array (85)
ChIP-seq (53)
Unknown experiment type (20)
Methylation profiling by array (17)
RNA-seq of non coding RNA (12)
MicroRNA profiling by array (11)
Genotyping by array (10)
Other (9)
DNA-seq (7)
RNAi profiling by array (6)
RNA-seq of coding RNA from single cells (6)
ChIP-chip by array (5)
Methylation profiling by high throughput sequencing (5)
ChIP-chip by tiling array (4)
Cell line - High-throughput sequencing (4)
Animal - One-color microarray (3)
Transcription profiling by RT-PCR (2)
MicroRNA profiling by high throughput sequencing (2)
CUT&RUN (2)
RNA-seq of total RNA (2)
Differential (1)
Cell line - Two-color microarray (1)
One-color microarray (1)
Whole chromosome random sequencing (1)
Transcription profiling by tiling array (1)
RIP-seq (1)
Proteomic profiling by array (1)
Genotyping by high throughput sequencing (1)

Release Date

2021 (648)
2022 (637)
2023 (486)
2020 (460)
2019 (390)
2018 (383)
2015 (367)
2014 (366)
2016 (354)
2024 (334)
2017 (333)
2025 (322)
2013 (278)
2012 (255)
2010 (210)
2011 (190)
2009 (157)
2008 (141)
2007 (72)
2006 (43)
2005 (39)
2026 (38)
2004 (24)
2003 (15)
2002 (14)
2001 (10)
2000 (9)
1998 (7)
1999 (5)
1997 (1)

Location

Taiwan (1)
France (1)

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Identification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia

Adult T-cell leukemia (ATL) is a highly aggressive T-cell malignancy characterized by human T-cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify novel targets in ATL cells in order to develop effective...

2025-02-03 | MTBLS11844 | MetaboLights

Identification of AK4 and RHOC as novel oncogenes addicted by adult T-cell leukemia

2025-02-03 | MTBLS11858 | MetaboLights

Broad and thematic remodeling of the surface glycoproteome on isogenic cells tranformed with driving proliferative oncogenes

The cell surface proteome, the surfaceome, is the interface for engaging the extracellular space in normal and cancer cells. Here we apply quantitative proteomics of N-linked glycoproteins to reveal how a collection of some 700 surface proteins is dramatically remodeled in an isogenic breast epithel...

ORGANISM(S): Homo sapiens (Human)

2020-04-08 | PXD017039 | Pride

Novel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers

Exposure to ionizing radiation during childhood markedly increases the risk of developing papillary thyroid cancer. We identified non-overlapping somatic driver mutations in all 26 cases of post-Chernobyl thyroid cancers we studied through candidate gene assays and next generation RNA-sequencing. We...

ORGANISM(S): Homo sapiens

2013-10-25 | E-GEOD-48850 | biostudies-arrayexpress

In Vitro Transformation of Primary Human CD34+ Cells by AML Fusion Oncogenes: Early Gene Expression Profiling Reveals Possible Drug Target in AML

Different fusion oncogenes in acute myeloid leukemia (AML) have distinct clinical and laboratory features suggesting different modes of malignant transformation. Here we compare the in vitro effects of representatives of major groups of AML fusion oncogenes on primary human CD34+ cells. For the 3 d ...

ORGANISM(S): Homo sapiens

2014-05-01 | E-GEOD-57194 | biostudies-arrayexpress

Gene Expression Regulation by Lung Cancer Oncogenes

PRJNA412863 | ENA

Suppression of poised oncogenes by ZMYND8 promotes chemo-sensitization

PRJNA606181 | ENA

SOX2 gene regulates the transcriptional network of oncogenes and affects tumorigenesis of human lung cancer cells

Recent studies demonstrated that cancer stem cells (CSCs) have higher tumorigenesis properties than those of differentiated cancer cells and that transcriptional factor-SOX2 plays a vital role in maintaining the unique properties of CSCs; however, the function and underlying mechanism of SOX2 in car...

ORGANISM(S): Homo sapiens

2012-08-31 | E-GEOD-36597 | biostudies-arrayexpress

Dynamics of host response to Merkel cell polyomavirus oncogenes

PRJNA540848 | ENA

Super-enhancer-associated oncogenes as novel therapeutic targets in osteosarcoma (ChIP-seq)

PRJNA555843 | ENA

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