a ‘multi-in-one’ strategy to saturate the phosphosite coverage from multiple-proteases by one-step enrichment and one-shot analysis in just over one hour, through data-independent acquisition (DIA)
Proteome analyses of human induced pluripotent cells (iPSC) were carried out by liquid chromatography–tandem mass spectrometry systems using meter-scale monolithic silica-C18 capillary columns without pre-fractionation. Tryptic peptides from five different iPSC lysates and three different fibroblast...
The proteome analysis of bile fluid represents a promising strategy to identify biomarker candidates for various diseases of the hepatobiliary system. However, to obtain substantive results in biomarker discovery studies large patient cohorts necessarily need to be analyzed. Consequently, this would...
