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TranscriptomicsCervical carcinoma-associated fibroblasts are DNA diploid and do not show evidence for somatic genetic alterations
Cancer-associated fibroblasts (CAFs) have been recognized as important contributors to cancer development and progression. However, opposing evidence has been published whether CAFs, in addition to epigenetic, also undergo somatic genetic alterations and whether these changes contribute to carcinoge...
ORGANISM(S): Homo sapiens 
2011-11-08 | E-GEOD-29143 | biostudies-arrayexpress
TranscriptomicsSimilar gene expression profiles of sporadic, PGL2-, and SDHD-linked paragangliomas
The similarity in gene-expression profiles suggest that PGL2, like SDHD, is involved in the functionality of the SDH complex, and that tumor formation in these three subgroups involves the same pathways as in SDH linked paragangliomas. We were not able to clarify the identity of PGL2 on 11q13. The l...
ORGANISM(S): Homo sapiens 
2008-12-10 | E-GEOD-12921 | biostudies-arrayexpress
TranscriptomicsGenome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma
Recurrent non-medullary thyroid carcinoma (NMTC) is a rare disease. We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). A validation cohort composed of benign and malignant (bo...
ORGANISM(S): Homo sapiens 
2012-08-29 | E-GEOD-31828 | biostudies-arrayexpress
TranscriptomicsCombined arrayCGH and SNP-loss of heterozygosity analysis in cervical cancer
BACKGROUND: Cervical carcinoma develops as a result of multiple genetic alterations. Different studies investigated genomic alterations in cervical cancer mainly by means of metaphase comparative genomic hybridization (mCGH) and microsatellite marker analysis for the detection of loss of heterozygos...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-8605 | biostudies-arrayexpress
TranscriptomicsHigh Resolution Copy Number Analysis of Paraffin Embedded Archival Tissue Using SNP BeadArrays
High density SNP microarrays provide insight into the genomic events that occur in diseases like cancer by their capability to measure both LOH and genomic copy numbers. Where currently available methods are restricted to the use of fresh frozen tissue, we now describe the design and validation of c...
ORGANISM(S): Homo sapiens 
2006-09-01 | E-GEOD-5347 | biostudies-arrayexpress
UnknownNo Adverse Programming by Post-Weaning Dietary Fructose of Body Weight, Adiposity, Glucose Tolerance, or Metabolic Flexibility.
Not available
S-EPMC5814917 | biostudies-literature
UnknownGenome-wide analysis of Ollier disease: Is it all in the genes?
Not available
S-EPMC3027091 | biostudies-literature
UnknownVascular aging in long-term survivors of testicular cancer more than 20 years after treatment with cisplatin-based chemotherapy.
Not available
S-EPMC7686327 | biostudies-literature
UnknownWestern Diet Triggers NLRP3-Dependent Innate Immune Reprogramming.
Not available
S-EPMC6324559 | biostudies-literature
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