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MetabolomicsSynergistic metabolism of salivary MUC5B in oral commensal bacteria during early biofilm formation

Bacterial metabolism in oral biofilms is comprised of complex networks of nutritional chains and biochemical regulations. These processes involve both intraspecies and interspecies networks as well as interactions with components from host saliva, gingival crevicular fluid, and dietary intake. In...

2023-10-30 | MTBLS8370 | MetaboLights
MetabolomicsSalivary MUC5B Modulation of Glucose Metabolism in Early Oral Biofilms
To investigate how early mono- and dual species biofilms of oral Actinomyces naeslundii and Streptococcus gordonii clinical isolates metabolized glucose in the presence of the complex salivary mucin MUC5B, this study employed NMR-based metabolomics with interpretation of network integration. Untarge...
2024-09-11 | MTBLS10078 | MetaboLights
GenomicsOral biofilm
Oral biofilm in Guided Bone Regenatarion
PRJNA699468 | ENA
TranscriptomicsTranscription analysis of biofilm grown in different depth
Using DNA-microarrays analysis 39 differentially expressed genes were identified in 200 vs. 100 microns biofilms, which might be associated with thickness of S. mutans biofilm. Using DNA-microarrays analysis 29 differentially expressed genes were identified in 400 vs. 100 microns biofilms of S. muta...
ORGANISM(S): Streptococcus mutans 
2010-05-06 | E-GEOD-12496 | biostudies-arrayexpress
ProteomicsHistone-like family of nucleoid structuring protein of A. actinomycetemcomitans promotes biofilm formation and alters protein dynamics of other species within multi-species biofilm
Aggregatibacter actinomycetemcomitans is a Gram-negative organism, strongly associated with aggressive forms of periodontitis. An important virulence property of A. actinomycetemcomitans is its ability to form tenacious biofilms that can attach to abiotic as well as biotic surfaces. The histone-like...
ORGANISM(S): Candida albicans (Yeast) Aggregatibacter aphrophilus Streptococcus mutans Streptococcus oralis Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) Fusobacterium nucleatum Veillonella dispar Actinomyces oris 
2018-06-05 | PXD008444 | Pride
Multi-species biofilm Hns A. actinomycetemcomitans Label-free quantification 
ProteomicsProtein expression patterns associated with sucrose-induced dysbiosis are conserved across taxonomically diverse oral microcosm biofilm models of dental caries.
The lesions of enamel caries can be considered as the outcome of dysbiotic changes in the biofilm community of supragingival dental plaque. Demineralization occurs as the cumulative outcome of repeated shifts towards a less diverse microbiota that produces and tolerates a low pH environment in tooth...
ORGANISM(S): Streptococcus mutans 19 
2016-01-04 | PXD003151 | Pride
Dental caries Metaproteomics Oral microbiome Galaxy-p Dysbiosis 
MetabolomicsBioactivities of Streptomyces spp. Against selected Oral Pathogens and In silico Streptenol B interaction on pgaB of Aggregatibacter actinomycetemcomitans
Periodontal disease is an inflammatory condition affecting the tissues supporting the teeth. Biofilm formation by oral pathogens such as Aggregatibacter actinomycetemcomitans (AA) and Pseudomonas aeruginosa (PA) contribute to persistent infections and antibiotic resistance. This study evaluated the ...
2026-06-23 | MTBLS14826 | MetaboLights
GenomicsOral cross-kingdom biofilm
Oral cross-kingdom biofilm Raw sequence reads
PRJNA434579 | ENA
MetabolomicsEvidence for proline utilisation by oral bacterial biofilms grown in saliva
Not available
ORGANISM(S): Multi-species non-defined biofilm consortium 
ST001433 | MetabolomicsWorkbench
UnknownEffects of stabilized hypochlorous acid on oral biofilm bacteria.
Not available
S-EPMC9487106 | biostudies-literature
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