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Chemotherapy may cause DNA damage within the oral mucosa of cancer patients leading to mucositis, a dose-limiting side effect for effective cancer treatment. We used whole genome gene expression analysis to identify cellular damage to the mucosal tissue occuring two days post induction chemotherapy ...
ORGANISM(S): Homo sapiens 
To reveal the molecular mechanisms underlying oral ulcerative mucositis-induced pain, we investigated putative pain-associated mediators, pain-related behaviors and gene modulation in a rat oral mucositis model. On day 1 after acetic acid treatment, the mucosal area showed slight redness and swellin...
ORGANISM(S): Rattus norvegicus 
Oral mucositis microbiome during allogeneic hematopoietic stem-cell transplant
Dynamic shifts in oral microbiota in patients with mucositis during radiotherapy.
Decreased salivary flow rates and/or changes in protein composition reported after autologous hematopoietic stem cell transplantation (ASCT) reduces the protective function of saliva. This might be associated with the development of oral mucositis (OM), an inflammation of the oral mucosa as a result...
ORGANISM(S): human oral bacteria ensemble Homo sapiens (Human) 
2023-07-10 | PXD033591 | Pride
Decreased salivary flow rates and/or changes in protein composition reported after autologous hematopoietic stem cell transplantation (ASCT) reduces the protective function of saliva. This might be associated with the development of oral mucositis (OM), an inflammation of the oral mucosa as a result...
ORGANISM(S): human oral bacteria ensemble Homo sapiens (Human) 
2023-07-10 | PXD033603 | Pride
Objective: Head and neck cancer (HNC) accounts for almost 850,000 new cases per year. Radiotherapy (RT) is used to treat the majority of these patients. A common side-effect of RT-treatment is onset of oral mucositis: a painful irritation and swelling in mouth, which decreases the quality of life an...
ORGANISM(S): Homo sapiens (Human) 
2023-06-09 | PXD040398 | Pride
Mirka Mucositis Samples
To reveal the molecular mechanisms underlying oral ulcerative mucositis-induced pain, we investigated putative pain-associated mediators, pain-related behaviors and gene modulation in a rat oral mucositis model. On day 1 after acetic acid treatment, the mucosal area showed slight redness and swellin...
ORGANISM(S): Rattus norvegicus 
2016-06-15 | GSE83349 | GEO
Chemotherapy may cause DNA damage within the oral mucosa of cancer patients leading to mucositis, a dose-limiting side effect for effective cancer treatment. We used whole genome gene expression analysis to identify cellular damage to the mucosal tissue occuring two days post induction chemotherapy ...
ORGANISM(S): Homo sapiens 
2009-01-01 | GSE10746 | GEO
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