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ProteomicsThe Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis - Yeast Data Set
Viruses often induce a complex rewiring of cellular physiology to maximize their propagation. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) expresses high amounts of the viral antagonistic protein Orf9b. Increased amounts and mutated versions of Orf9b were found to correlate with ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-08-30 | PXD039850 | Pride
Orf9b Mitochondrial import 
Proteomicsiotin-streptavidin affinity purification mass spectrometry of proteins in human 293T cell using bioinylated Orf9b
COVID-19, caused by the new RNA virus strain SARS-CoV-2, is a serious acute respiratory disease. One of the prominent feature of SARS-COV-2 in terms of immune responses is that it triggers very low level responses of IFN-I in cells or COVID-19 patients. Previously SARS-CoV Orf9b were reported to be ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019803 | Pride
Ap-ms Human 293t cell Silac Sars-cov-2 orf9b 
ProteomicsProteins interacting with SARS-CoV-2 ORF9b
Identification of the host factors trigger ORF9b degradation
ORGANISM(S): Homo Sapiens 
2024-02-23 | PXD050055 |
ProteomicsHEK293 WT and TOM70 KD cell lines expressing HA-tagged Orf9b grown on glucose media
Comparison of whole cell proteome of HEK293 WT and TOM70 KD cell lines expressing HA-tagged Orf9b grown on glucose media.
ORGANISM(S): Homo sapiens (Human) 
2023-08-30 | PXD040491 | Pride
Orf9b Tom70 Glucose 
ProteomicsHEK293 WT and TOM70 KD cell lines expressing HA-tagged Orf9b grown on galactose media
Comparison of whole cell proteome of HEK293 WT and TOM70 KD cell lines expressing HA-tagged Orf9b grown on galactose media
ORGANISM(S): Homo sapiens (Human) 
2023-08-30 | PXD040494 | Pride
Orf9b Tom70 Galactose 
UnknownThe Orf9b protein of SARS-CoV-2 modulates mitochondrial protein biogenesis.
Not available
S-EPMC10491932 | biostudies-literature
UnknownPredictable fold switching by the SARS-CoV-2 protein ORF9b.
Not available
S-EPMC8242659 | biostudies-literature
UnknownStructural characterization of SARS-CoV-2 dimeric ORF9b reveals potential fold-switching trigger mechanism.
Not available
S-EPMC9527070 | biostudies-literature
UnknownThe Deubiquitinase USP29 Promotes SARS-CoV-2 Virulence by Preventing Proteasome Degradation of ORF9b.
Not available
S-EPMC9239186 | biostudies-literature
UnknownCoupled equilibria of dimerization and lipid binding modulate SARS Cov 2 Orf9b interactions and interferon response.
Not available
S-EPMC11870501 | biostudies-literature
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