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ORMDL proteins are essential negative regulators of the serine palmitoyltransferase (SPT) complex, thereby controlling the rate of de novo sphingolipid synthesis. Although mammalian ORMDL proteins undergo rapid turnover, the mechanisms regulating their stability are not completely understood, with c...
ORGANISM(S): Homo sapiens (Human) 
2026-03-16 | PXD067431 | Pride
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