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TranscriptomicsInfluence of organic cultivation on potato transcriptome
Analysis of the transcription profiles in tubers of S. tuberosum L. cv. Ditta grown in two experimental seasons under either conventional or organic crop management.
ORGANISM(S): Solanum tuberosum 
2017-05-11 | E-MTAB-3367 | biostudies-arrayexpress
UnknownThe Algal Antioxidant Carotenoid Diatoxanthin as a Modulator of Inflammation and Angiogenesis in Triple-Negative Breast Cancer Cells
Not available
S-EPMC12938071 | biostudies-literature
TranscriptomicsGlobal changes in gene expression in dermal fibroblasts with in vivo and in vitro deletion of the RBP-Jk gene
It is currently unclear whether tissue changes surrounding multifocal epithelial tumors are a cause or consequence of cancer. Here, we provide evidence that loss of mesenchymal Notch/CSL signaling causes tissue alterations, including stromal atrophy and inflammation, which precede and are potent tri...
ORGANISM(S): Mus musculus 
2012-06-11 | E-GEOD-36359 | biostudies-arrayexpress
TranscriptomicsA platform of patient-derived tumor xenografts (EOC-xenografts) to recapitulate the clinicopathology and genetic alterations of ovarian cancer
Epithelial ovarian cancer (EOC) is the most lethal gynecological malignancy. On the basis of its histopathology and molecular-genomic changes ovarian cancer has been divided into subtypes, each with distinct biology and outcome. The aim of this study was to develop a panel of patient-derived EOC-xen...
ORGANISM(S): Homo sapiens 
2015-01-07 | E-GEOD-56920 | biostudies-arrayexpress
TranscriptomicsmiRNA profiling of mixoid liposarcoma cell lines sensitive and resistant to trabectidin
This investigation aims at identifying differentially expressed miRNA between two cell lines, MLS 402-91 (sensitive to trabectidin) and MLS 402-91/ET (resistant to trabectidin).
ORGANISM(S): Homo sapiens 
2012-06-05 | E-MTAB-695 | biostudies-arrayexpress
GenomicsPhysical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution [ChIP-seq]
Senescence of stromal fibroblasts has been linked to establishment of cancer associated fibroblasts (CAF) and aging-associated increase of tumors. However, in clinically occurring carcinomas, density and proliferation of CAFs are frequently increased rather than decreased. We previously showed that ...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-59942 | biostudies-arrayexpress
TranscriptomicsApoptosis, autophagy and senescence protect BRAFV600E nevi from malignant transformation
The oncogenic mutation BRAFV600E is a common event in nevi and melanomas, which are aggressive skin tumors characterized by MAPK signaling pathway activation. It has been observed that mutated benign melanocytic lesions can remain unchanged for decades, but also proliferate or undergo oncogene-ind...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-23976 | biostudies-arrayexpress
TranscriptomicsHuman prostate carcinoma cell line 22Rv1 overexpressing ESE1
Activation of the inflammatory circuits occurs frequently in cancer cells. However the molecular details linking inflammation to transformation and progression are still unknown. In this study we report for the first time, that activation of the ETS factor ESE1 is a key event connecting inflammatory...
ORGANISM(S): Homo sapiens 
2013-06-20 | E-GEOD-39668 | biostudies-arrayexpress
TranscriptomicsPhysical and functional CSL-p53 interactions underlie control of cancer stromal cell evolution [RNA-seq]
Senescence of stromal fibroblasts has been linked to establishment of cancer associated fibroblasts (CAF) and aging-associated increase of tumors. However, in clinically occurring carcinomas, density and proliferation of CAFs are frequently increased rather than decreased. We previously showed that ...
ORGANISM(S): Homo sapiens 
2015-08-24 | E-GEOD-65473 | biostudies-arrayexpress
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