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ProteomicsComparative intraindividual proteomic analysis of osteogenic differentiated adipose tissue-derived and bone marrow-derived mesenchymal stem cells reveals integrin expression profile as distinctive feature
The treatment of bone defects caused by infection, trauma or neoplasms remains a clinical challenge. Autologous bone transplantation is limited by availability, donor site morbidity and surgical risk factors. This has given rise to stromal/stem-cell based therapy. Bone marrow derived stromal cells (...
ORGANISM(S): Homo sapiens (Human) 
2021-06-09 | PXD015223 | Pride
Dia-based proteomics Bone defect Osteogenic differentiated human stem cells Integrin 
TranscriptomicsGenome-wide CpG methylation during osteogenic and myogenic differentiation from adipose- derived stem cells.
In the current study, we have performed a high-throughput CpG methylation analysis of well characterized and defined populations of human adipose-derived stem cells (hASCs) before and after in vitro induction of osteogenic and myogenic differentiation that allows identifying DNA methylation- regulat...
ORGANISM(S): Homo sapiens 
2014-01-02 | E-GEOD-33896 | biostudies-arrayexpress
TranscriptomicsRNA microarray of osteogenic differentiated human mesnechymal stem cells treated with zoledronate againt controls
To see the effect of zoledronate on the osteogenic differentiation of human mesenchymal stem cells. Cells were first cultured in normal media until enough cells were obtained. Then the cells were differentiated into ostepbalst under the effect of low concentration of zoledronate.
ORGANISM(S): Homo sapiens 
2020-01-16 | E-MTAB-7459 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human osteoblasts differentiated from human mesenchymal stem cells and treated with three bioactive peptides
Effects of bioactive peptides IPP(Ile-Pro-Pro), VPP (Val-Pro-Pro), and LKP(Leu-Lys-Pro) on gene expression of osteoblast differentiated from human mesenchymal stem cells. Experimental design types: compound treatment and augmented reference design.
ORGANISM(S): Homo sapiens 
2008-01-23 | E-MEXP-885 | biostudies-arrayexpress
TranscriptomicsThe human nose harbours a niche of olfactory ecto-mesenchymal stem cells displaying neurogenic and osteogenic properties
We previously identified multipotent stem cells within the lamina propria of the human olfactory mucosa, located in the nasal cavity. We also demonstrated that this cell type differentiates into neural cells and improves locomotor behavior after transplantation in a rat model of Parkinson’s diseas...
ORGANISM(S): Homo sapiens 
2010-10-08 | E-GEOD-24598 | biostudies-arrayexpress
ProteomicsExtracellular vesicles from osteogenic differentiated human BMSCs
Pathological processes like osteoporosis or steroid-induced osteonecrosis of the hip are accompanied by increased bone marrow adipogenesis. Such disorder of adipogenic/osteogenic differentiation, which affects also bone marrow derived mesenchymal stem cells (BMSCs) contributes to bone loss during ag...
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD035845 | Pride
Ev Bmsc 
ProteomicsA spiked human proteomic dataset from human osteogenic differentiated BMSCs and ASCs for use as a spectral library, for modelling pathways as well as protein mapping
This article describes a mass spectrometry data set generated from osteogenic differentiated bone marrow stromal cells (BMSCs) and adipose tissue derived stromal cells (ASCs) of a 24-year old healthy donor spiked with iRT peptides. Cells have been identified via FACS-Analysis positive for CD90 and C...
ORGANISM(S): Homo sapiens (Human) 
2019-10-22 | PXD015026 | Pride
Data-independent acquisition analysis Nanohplc-esi-ms/ms Osteogenic differentiated mesenchymal stem cells 
TranscriptomicsMicroarray Expression Data from Haematopoietic Differentiated Human Embryonic Stem Cells
The underlying mechanisms which are responsible and govern early haematopoietic differentiation during development are poorly understood. Gene expression comparison between pluripotent human embryonic stem cells and earliest haematopoietic progenitors may reveal novel transcripts and pathways and p...
ORGANISM(S): Homo sapiens 
2012-01-06 | E-GEOD-29115 | biostudies-arrayexpress
ProteomicsDynamic proteomic profiling of human periodontal ligament stem cells during osteogenic differentiation
Human periodontal ligament stem cells (hPDLSCs) are ideal seed cells for periodontal regeneration. To better understand the dynamic protein profiles during hPDLSCs osteogenic differentiation, we conducted a quantitative proteomics to reveal the temporal protein expression pattern during this process...
ORGANISM(S): Homo sapiens (Human) 
2021-02-11 | PXD020908 | Pride
Human Dynamic expression Tmt Periodontal 
TranscriptomicsTranscription profiling of human adipose derived stem cells before induction and at two time points after induction of differentiation
Adipose derived stem cells were induced for two time points (Day 2 and 28) and compared to the corresponding uninduced sample from the same human donor. A total of 20 biological replicates were conducted. Transcription profiling done with Affymetrix U133 Plus 2.0 arrays.
ORGANISM(S): Homo sapiens 
2007-10-10 | E-MEXP-1216 | biostudies-arrayexpress
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