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MetabolomicsEndo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation (Lipid Samples)
Not available
ORGANISM(S): Homo sapiens 
ST002142 | MetabolomicsWorkbench
MetabolomicsEndo- and Exometabolome Crosstalk in Mesenchymal Stem Cells Undergoing Osteogenic Differentiation (Media Samples)
Not available
ORGANISM(S): Homo sapiens 
ST002143 | MetabolomicsWorkbench
ProteomicsThe novel tRF-23 promotes osteogenic differentiation of hBMSCs and protects against bone loss in ovariectomized mice
The pathogenesis of osteoporosis is closely related to the impaired human bone marrow-derived stromal cells (hBMSCs) osteogenic differentiation. No studies to date, however, have established whether tRNA-derived fragments (tRFs) can influence osteogenic differentiation of hBMSCs or the onset of oste...
ORGANISM(S): Homo sapiens (Human) 
2026-01-19 | PXD067728 | Pride
Trf-23 Osteogenic differentiation Hbmscs Osteoporosis 
ProteomicsDifferent osteogenic differentiation behavior of canine mesenchymal stem cells derived from bone marrow and dental pulp: the proteomics profile
Although various sources of cMSCs show similar characteristics, they are different in osteogenic potential due to their original cellular sources. Thus, this study was designed to globally explore and analyze the in vitro differentiation potential and behavior of canine bone-marrow derived mesenchym...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2021-09-08 | PXD015512 | Pride
Osteogenic differentiation Canine bone-marrow derived mesenchymal stem cells (cbm-mscs) Canine dental pulp stem cells (cdpscs) Systems biology 
ProteomicsCrenigacestat inhibits osteogenic differentiation of human valve interstitial cells and seems promising for treatment of cardiovascular calcification
Vascular calcification is common pathology various forms of which presented in the half of humans. Calcific aortic valve disease (CAVD) is one of the most dangerous forms of vascular calcification. Despite high mortality there is no target therapy against CAVD. Thus, we tested crenigacestat (LY30394...
ORGANISM(S): Homo sapiens (Human) 
2022-10-04 | PXD029632 | Pride
Valve intersticial cells Timstof pro Vascular calcification Ly3039478 Notch inhibitors Crenigacestat Calcific aortic valve disease Shotgun proteomics 
TranscriptomicsDiverse effects of cyclic AMP variants on osteogenic and adipogenic differentiation of human mesenchymal stromal cells
Osteogenic differentiation of human mesenchymal stromal cells (hMSCs) may potentially be used in cell-based bone tissue-engineering applications to enhance the bone-forming potential of these cells. Osteogenic differentiation and adipogenic differentiation are thought to be mutually exclusive, and a...
ORGANISM(S): Homo sapiens 
2018-08-05 | E-MTAB-7038 | biostudies-arrayexpress
ProteomicsComparative analysis of proteomes and secretomes of human mesenchymal stem cells isolated from six sources during osteogenic differentiation
Ability to perform osteogenic differentiation is one of the minimal criteria of mesenchymal stem cells (MSCs). Still, it is generally unknown whether osteogenic differentiation is universal cell fate or various phenotypically similar cell states. Besides this, MSCs and their secretomes are actively ...
ORGANISM(S): Homo sapiens (Human) 
2023-11-05 | PXD037320 | Pride
Msc Timstof pro Osteogenic differeniation Secretome 
ProteomicsConditioned medium from human iPSC-derived mesenchymal progenitors: Effect of extended progenitor cultivation vs. osteogenic pre-differentiation on the medium stimulatory activity
Human induced pluripotent stem cells provide an unlimited, scalable source of youthful tissue progenitors and secretome for regenerative therapies. The aim of our study was to assess the potential of conditioned medium (CM) derived from hiPSC-mesenchymal progenitors (hiPSC-MPs) to stimulate osteogen...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052766 | Pride
Human ipscs Osteogenic differentiation Mesenchymal progenitors Proteomic analysis Conditioned medium Human bone marrow mesenchymal stromal cells Secretome Aging 
ProteomicsTemporal Profiling of Epitranscriptomic Reader, Writer and Eraser Proteins during Osteogenic Differentiation of Human Embryonic Stem Cells
Osteogenesis is the process of bone formation and is modulated by multiple regulatory networks. With the rapid development of the epitranscriptomics field, RNA modifications and their reader, writer, and eraser (RWE) proteins are shown to be involved in the regulation of various biological processes...
ORGANISM(S): Homo sapiens (Human) 
2023-05-23 | PXD039249 | Pride
Epitranscriptomic reader Writer and eraser Osteogenesis 
ProteomicsMulti-omics identification of key targets for the osteogenic differentiation of human bone marrow mesenchymal stromal cells under oxidative stress
Background: Human bone marrow mesenchymal stromal cells (hBMSCs) are multipotent stromal cells capable of osteogenic differentiation, making them a promising cell source for bone tissue engineering and regenerative medicine. Identifying key factors that regulate hBMSCs osteogenic differentiation is ...
ORGANISM(S): Homo sapiens (Human) 
2026-03-09 | PXD067569 | Pride
Osteogenic differentiation Proteomics Bone marrow mesenchymal stromal cells Oxidative stress Transcriptomics 
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