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TranscriptomicsPtrA is required for coordinate regulation of gene expression during phosphate depletion in a marine Synechococcus
The genome of the marine Synechococcus sp. WH8102 displays a minimal regulatory network yet physiological and molecular responses of this organism are tuned to episodic limitation for nitrogen and phosphorus. Microarray analyses have demonstrated a key role for the two-component regulatory system, P...
ORGANISM(S): Synechococcus sp. WH 8102 
2010-04-08 | E-GEOD-18511 | biostudies-arrayexpress
TranscriptomicsExpression Data from Normal or Tumor Fibroblasts With or Without Ets2
The mechanisms involved in epithelium-stroma interactions remain poorly understood, despite the importance of the microenvironment during tumorigenesis. Here, we studied the role of the Ets2 transcription factor in tumor-associated fibroblasts in the MMTV-PyMT mammary tumor model. Inactivation of ...
ORGANISM(S): Mus musculus 
2014-03-19 | E-GEOD-16989 | biostudies-arrayexpress
ProteomicsJurkat extracellular vesicle fractionation profiling
Extracellular vesicles are a mixture of particles of variable size and subcellular origin. To characterize the different vesicle species further, we applied differential centrifugation and profiling to Jurkat cell conditioned medium. The three step centriguation gradient yielded sufficient partial s...
ORGANISM(S): Homo sapiens (Human) 
2021-02-26 | PXD019074 | Pride
Extracellular vesicles Profiling Silac Fractionation Jurkat Differential centrifugation 
UnknownConvergent CDR3 homology amongst Spike-specific antibody responses in convalescent COVID-19 subjects receiving the BNT162b2 vaccine.
Not available
S-EPMC8897198 | biostudies-literature
UnknownUnbiased proteomic profiling of host cell extracellular vesicle composition and dynamics upon HIV-1 infection.
Not available
S-EPMC8047442 | biostudies-literature
ProteomicsAn interactive predictor to reassess the specific protein compositions of HIV-1 and extracellular vesicles
HIV-infected T cells secrete simultaneously viral particles and small extracellular vesicles (sEVs) including MVB-derived exosomes and plasma membrane-derived EVs. sEVs and HIV share many physical and chemical characteristics, which makes their separation difficult.. Here, we used a global and un-bi...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD016626 | Pride
Exosomes Extracellular vesicles Hiv-1 
UnknownComparable safety and non-inferior immunogenicity of the SARS-CoV-2 mRNA vaccine candidate PTX-COVID19-B and BNT162b2 in a phase 2 randomized, observer-blinded study.
Not available
S-EPMC10912344 | biostudies-literature
MetabolomicsChemotaxis shapes the microscale organization of the ocean’s microbiome

The capacity of planktonic marine microorganisms to actively seek out and exploit microscale chemical hotspots has been widely theorized to affect ocean-basin scale biogeochemistry, but has never been examined comprehensively in situ among natural microbial communities. Here, using a field-based ...

2022-02-15 | MTBLS1980 | MetaboLights
UnknownEts2 in tumor fibroblasts promotes angiogenesis in breast cancer.
Not available
S-EPMC3745457 | biostudies-literature
UnknownVaccination against SARS-CoV-2 provides low-level cross-protection against common cold coronaviruses in mouse and non-human primate animal models.
Not available
S-EPMC11853048 | biostudies-literature
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