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GenomicsDrosophila melanogaster
Gene expression analyses in otefin mutant Drosophila ovaries
PRJNA376599 | ENA
TranscriptomicsGene expression analyses in otefin mutant Drosophila ovaries
LEM Domain proteins are key components of the nuclear lamina. Mutations in LEM-D proteins cause dystrophic diseases associated with compromised adult stem cells, yet it remains unclear how LEM-D proteins support stem cell function. Studies described here use the homologue of the LEM-D protein emerin...
ORGANISM(S): Drosophila melanogaster 
2018-07-03 | GSE95309 | GEO
UnknownDrosophila male and female germline stem cell niches require the nuclear lamina protein Otefin.
Not available
S-EPMC4902716 | biostudies-literature
UnknownSurvival of Drosophila germline stem cells requires the chromatin-binding protein Barrier-to-autointegration factor.
Not available
S-EPMC7240298 | biostudies-literature
UnknownNuclear lamina dysfunction triggers a germline stem cell checkpoint.
Not available
S-EPMC6160405 | biostudies-literature
UnknownRecruitment of BAF to the nuclear envelope couples the LINC complex to endoreplication.
Not available
S-EPMC7758627 | biostudies-literature
ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041032 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041030 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
ProteomicsIdentification of PP2A-B55 targets in Drosophila uncovers regulation of Emerin during nuclear envelope reassembly
Entry into mitosis is triggered by mitotic kinases that phosphorylate multiple proteins to induce profound cellular changes including nuclear envelope breakdown, chromosome condensation and spindle assembly. Conversely, mitotic exit requires protein dephosphorylation as cells return to their interph...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2023-08-10 | PXD041091 | Pride
Otefin Pp2a Baf Lamin Nuclear envelope Mitotic exit Mitosis Emerin 
UnknownIdentification of PP2A-B55 targets uncovers regulation of emerin during nuclear envelope reassembly in Drosophila.
Not available
S-EPMC10353892 | biostudies-literature
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