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TranscriptomicsMethotrexate resistant Leishmania strains
This SuperSeries is composed of the following subset Series: GSE9947: Transcriptional analysis of Leishmania infantum methotrexate resistant strains using full-genome DNA microarrays GSE9948: Transcriptional analysis of Leishmania major methotrexate resistant strains using full-genome DNA microarray...
ORGANISM(S): Leishmania infantum 
2010-05-25 | E-GEOD-9949 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Leishmania major methotrexate resistant strains using full-genome DNA microarrays
Transcriptional analysis of the drug resistant strain L. major MTX60.4 compared to the wild-type strain LV39 The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.major LV39 Keywords: drug resistance Two-condition experiment, resistant strain MTX60.4 vs wild-type ...
ORGANISM(S): Leishmania major 
2010-05-25 | E-GEOD-9948 | biostudies-arrayexpress
TranscriptomicsTranscriptional analysis of Leishmania infantum methotrexate resistant strains using full-genome DNA microarrays
Transcriptional analysis of the drug resistant strain L. infantum MTX20.5 compared to the wild-type strain The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L. infantum Keywords: drug resistance Two-condition experiment, resistant strain MTX20.5 vs wild-type. Fo...
ORGANISM(S): Leishmania infantum 
2010-05-25 | E-GEOD-9947 | biostudies-arrayexpress
TranscriptomicsComparative Genomic Hybridization of Leishmania major methotrexate resistant strains vs wild-type LV39
CGH analysis of the drug resistant strain L. major MTX60.4 vs the wild-type strain LV39 The full-genome DNA microarrays includes one 70-oligonucleotides probe for each gene of L.major LV39 Keywords: drug resistance Two-condition experiment, resistant strain MTX60.4 vs wild-type LV39. Three biologic...
ORGANISM(S): Leishmania major 
2008-05-31 | E-GEOD-11623 | biostudies-arrayexpress
TranscriptomicsEngagement of the aryl hydrocarbon receptor in M. tuberculosis-infected macrophages has pleiotropic effects on innate immune signaling
Understanding the mechanisms of host macrophage responses to M. tuberculosis (M.tb.) is essential for uncovering potential avenues of intervention to boost host resistance to infection. Macrophage transcriptome profiling revealed M.tb. infection strongly induced expression of several enzymes control...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70200 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of strains of Leishmania infantum, Leishmania major and Leishmania tarentolae
The genomic DNAs of strains JPCM5 and 263 of L. infantum, strains LV39 and Friedlin of L. major and strains Parrot-TarII and S125 of L. tarentolae were used in comparative genomic hybridizations to reveal the intra-species and inter-species gene content, and to validate L. tarentolae Parrot-TarII ge...
ORGANISM(S): Leishmania tarentolae 
2011-10-20 | E-GEOD-27184 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant [Comparative Genomic Hybridization (DNA) profiling]
Drug resistance is a major public health challenge in Leishmaniasis chemotherapy, particularly in the case of emerging Leishmania/HIV-1 co-infections. Recently, we have delineated the mechanism of cell death induced by the HIV-1 protease inhibitor, Nelfinavir, in the Leishmania parasite. In order to...
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42195 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant [RNA expression profiling]
Drug resistance is a major public health challenge in Leishmaniasis chemotherapy, particularly in the case of emerging Leishmania/HIV-1 co-infections. Recently, we have delineated the mechanism of cell death induced by the HIV-1 protease inhibitor, Nelfinavir, in the Leishmania parasite. In order to...
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42196 | biostudies-arrayexpress
TranscriptomicsLeishmania donovani amastigotes: Nelfinavir (NFV)-sensitive (control) vs Nelfinavir-resistant
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Leishmania donovani 
2013-06-27 | E-GEOD-42197 | biostudies-arrayexpress
UnknownStandard care versus protocol based therapy for new onset Pseudomonas aeruginosa in cystic fibrosis.
Not available
S-EPMC4059359 | biostudies-literature
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