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Secretion of outer membrane vesicles (OMV) presents an important phenomenon in Gram-negative bacteria and they play multiple roles in their lifestyle including virulence and host-pathogen interaction. Francisella tularensis secretes unusually shaped tubular OMV. We here present a proteomic compariso...
ORGANISM(S): Francisella tularensis Francisella tularensis subsp. tularensis SCHU S4 Francisella tularensis subsp. holarctica FSC200 
2021-02-08 | PXD022406 | Pride
Francisella tularensis is a Gram-negative, facultative intracellular bacterium, causing a severe disease known as tularemia. It is known to secrete unusually shaped nanotubular outer membrane vesicles (OMV) loaded with number of virulence factors and immunoreactive proteins. In this study the nanotu...
ORGANISM(S): Francisella tularensis subsp. holarctica Francisella tularensis subsp. holarctica FSC200 
2019-09-30 | PXD013074 | Pride
Here, we illustrate the proteomic composition and hydrolytic capacity of outer membrane vesicles (OMVs) produced by F. succinogenes during growth on Avicel cellulose and show that the OMVs are equipped with a highly versatile polysaccharide-degrading machinery. Proteomic assessment identified an enr...
ORGANISM(S): Fibrobacter succinogenes subsp. succinogenes S85 
2017-06-30 | PXD005442 | Pride
Outer membrane vesicles (OMVs) produced by Gram-negative bacteria are mediators of cell survival and pathogenesis by facilitating nutrient transport, virulence factor dissemination, and resistance to antimicrobials. Studies of OMV properties often focus on hypervesiculating Escherichia coli mutants ...
ORGANISM(S): Escherichia coli 
2021-09-09 | PXD022786 | Pride
Differential proteomic analysis of outer membrane vesicles from Bordetella pertussis (two strains: Bvg+ and Bvg-)
ORGANISM(S): Bordetella Pertussis (ncbitaxon:520) 
2017-11-09 | MSV000081702 | MassIVE
Aggregatibacter actinomycetemcomitans is an oral and systemic pathogen associated with aggressive forms of periodontitis, and with endocarditis. Outer membrane vesicles (OMVs) released by this species have been demonstrated to deliver effector proteins such as cytolethal distending toxin (CDT) and l...
ORGANISM(S): Aggregatibacter actinomycetemcomitans (Actinobacillus actinomycetemcomitans) (Haemophilus actinomycetemcomitans) 
2015-09-21 | PXD002509 | Pride
The project aims to elucidate mechanisms driving P. aeruginosa response to sex steroids hormones. An experiment involving outer membrane vesicles (OMV) extraction combined with Mass spectroscopy was performed to identify differences in P. aeruginosa OMVs proteins produced while being exposed to estr...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2021-09-08 | PXD019470 | Pride
Bacterial outer membrane vesicles (OMVs) have important biological roles in pathogenesis and intercellular interactions, but a general mechanism of OMV formation is lacking. Here we show that the VacJ/Yrb ABC transport system, a proposed phospholipid (PL) transporter, is involved in OMV formation. D...
ORGANISM(S): Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 
2016-01-27 | PXD003249 | Pride
Large-scale production of bacterial extracellular vesicles is a hurdle for their development as novel cancer immunotherapeutic agents. Here, we developed manufacturing processes for mass production of Escherichia coli EVs known as outer membrane vesicles (OMVs). We present a comprehensive proteome o...
ORGANISM(S): Escherichia coli Bacteria 
2023-10-24 | PXD043119 | Pride
At present, the function of Fusobacterium nucleosocci outer membrane vesicles under normal intestinal environmental pH conditions has been mainly studied, but there are few studies related to the function of Fusobacterium nucleosius outer membrane vesicles under cancer microenvironment pH conditions...
ORGANISM(S): Fusobacterium Nucleatum Subsp. Vincentii 
2022-10-18 | PXD037520 |
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