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ProteomicsDe-2-hydroxyisobutyrylation of clusterin attenuates neuropathology and memory deficits in an Alzheimer's disease mouse model
Backgroud Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disorder for which there is currently no cure, representing a serious clinical challenge. Lysine 2-hydroxyisobutyrylation (Khib) is a newly discovered post-translational modification that has been found to be wid...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-04 | PXD066261 | Pride
Clusterin Adeno-associated viruse 2-hydroxyisobutyrylation Post-translational modification Alzheimer's disease 
UnknownGenotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.
Not available
S-EPMC7439928 | biostudies-literature
ProteomicsChronic exposure to low-level lipopolysaccharide dampens influenza-mediated inflammatory response via A20 and PPAR network
Influenza A virus (IAV) infection leads to severe inflammation, and while epithelial-driven inflammatory responses occur via activation of NF-B, the factors that modulate inflammation, particularly the negative regulators are less well-defined. In this study we show that A20 is a crucial molecular...
ORGANISM(S): Homo Sapiens 
2022-07-29 | PXD035611 |
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